Current and Emerging Therapeutic Strategies for Limited- and Extensive-Stage Small-Cell Lung Cancer.

Background: Small-cell lung cancer (SCLC) is a highly aggressive neuroendocrine malignancy characterized by rapid growth, early metastatic dissemination, and a dismal prognosis. For decades, treatment paradigms remained largely stagnant, particularly for extensive-stage disease (ES-SCLC). However, the last five years have witnessed a significant evolution in the therapeutic landscape.

Incidence, Risk Factors, and Outcomes of Recurrent Laryngeal Nerve Injury and Dysphonia Following Anterior Cervical Spine Surgery: A Systematic Review and Meta-Analysis.

Anterior cervical spine surgery (ACSS) is an effective treatment for various cervical spine conditions but carries a risk of recurrent laryngeal nerve (RLN) injury and dysphonia. This systematic review and meta-analysis aimed to evaluate the incidence of these complications and their associated risk factors. An analysis of 17 studies involving 5,706 patients revealed a pooled RLN injury incidence of 3.

Successful Non-fusion Management of a Healed Pediatric Odontoid Synchondrosis Fracture: A Case Report.

Odontoid synchondrosis fractures are rare pediatric spinal injuries that pose significant diagnostic and treatment challenges. These fractures, typically occurring in the C-2 vertebra, often result from high-energy trauma and are difficult to diagnose due to subtle radiographic findings. We present the case of a 4-year-old male who sustained a head injury while playing on a trampoline.