Experimental technique for measuring radial coherence.

Coherence refers to correlations between field vibrations at two separate points in degrees of freedom such as space, time, and polarization. In the context of space, coherence theory has been formulated between two transverse positions which can be described either in the Cartesian coordinates or in the cylindrical coordinates. When expressed in cylindrical coordinates, spatial coherence is described in terms of azimuthal and radial coordinates.

Pulse characterization at the single-photon level through chronocyclic -function measurements.

The characterization of the complex spectral amplitude, that is, the spectrum and spectral phase, of single-photon-level light fields is a crucial capability for modern photonic quantum technologies. Since established pulse characterization techniques are not applicable at low intensities, alternative approaches are required. Here, we demonstrate the retrieval of the complex spectral amplitude of single-photon-level light pulses through measuring their chronocyclic  -function.

Role of Intraoperative Neuromonitoring to Identify External Branch of Superior Laryngeal Nerve During Thyroidectomy.

To evaluate the role of Intraoperative neuromonitoring (IONM) in visual and functional identification of external branch of superior laryngeal nerve (EBSLN) during thyroidectomy operation, 2. To identify the anatomical variations of EBSLN according to Cernea classification. This is a prospective observational study done on 30 patients who underwent thyroidectomy operation at the Department of Otorhinolaryngology in a tertiary medical institute.

Coherence in the radial degree of freedom.

Coherence quantifies the statistical fluctuations in an optical field and has been extensively studied in the space, time, and polarization degrees of freedom. In the context of space, coherence theory has been formulated between two transverse positions as well as between two azimuthal positions, referred to as transverse spatial coherence and angular coherence, respectively. In this paper, we formulate the theory of coherence for optical fields in the radial degree of freedom and discuss the associated concepts of coherence radial width, radial quasi-homogeneity, and radial stationarity with some physically realizable examples of radially partially coherent fields.

Low level of BRCA2 in peripheral blood lymphocytes is associated with an increased risk for head and neck squamous cell carcinoma (HNSCC) in a population of North-East India: a case-control study.

Background: We investigated the role of DNA repair proteins breast cancer susceptibility 2 (BRCA2), xeroderma pigmentosum group D (XPD) and apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) in determining the risk for head and neck squamous cell cancer (HNSCC) in a case-control study from North-East India.

Methods: Expression of , and genes in the matched tumour, normal adjacent tissue (NAT) and blood of 12 HNSCC patients and blood of 8 age- and gender-matched controls was determined by quantitative real-time PCR. Results were validated by expression analysis of the corresponding proteins in the peripheral blood lymphocytes (PBLs) of 228 subjects (106 patients and 122 controls) by a slot-blot immunoassay.

Comparative Study of Parathyroid Identification Techniques Using Zuckerkandl's Tubercle Versus Parathyroid Arterial Supply as Intra-Operative Markers.

Thyroid surgeons should be able to identify factors that prevent parathyroid damage. The aim of the study was (i) to compare the effectiveness of using Zuckerkandl's Tubercle (ZT) versus superior thyroid artery (STA) and inferior parathyroid artery (ITA) as markers for identification of superior and inferior parathyroid glands and (ii) to demonstrate a series of detailed, logical and orderly operative steps to identify ZT during thyroidectomy operation. This 1-year prospective observational study was carried out in the Department of Otolaryngology in a tertiary medical institute.

Propagation-induced revival of entanglement in the angle-OAM bases.

Although the continuous-variable position-momentum entanglement of photon pairs produced by parametric down-conversion has applicability in several quantum information applications, it is not suitable for applications involving long-distance propagation. This is because entanglement in the position-momentum bases, as seen through Einstein-Podolsky-Rosen (EPR)-correlation measurements, decays very rapidly with photons propagating away from the source. In contrast, in this article, we show that in the continuous-variable bases of angle-orbital angular momentum (OAM), the entanglement, as seen through EPR-correlation measurements, exhibits a remarkably different behavior.

Altered expression of junctional proteins as a potential biomarker in oral precancerous and cancerous patients.

Due to a lower survival rate in patients with advanced clinical stages of oral cancer, discovering a biomarker that could diagnose and predict disease progression is vital. Cell-cell junctional proteins play a crucial role in the maintenance of tissue architecture but are often deregulated in different cancer. The present study investigates the expression of cell-cell junctional proteins : e-cadherin (E-cad) and zonula occludens-1 (ZO-1) in oral precancerous (OED) and cancerous (OSCC) patients to monitor if they can serve as practicable molecular markers.

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA.

Head and neck cancers are highly prevalent in south-east Asia, primarily due to betel nut chewing. Arecoline, the primary alkaloid is highly carcinogenic; however its role in promoting tumorigenesis by disrupting junctional complexes and increasing risk of metastasis is not well delineated. Subsequently, the effects of low and high concentrations of arecoline on the stability of tight junctions and EMT induction were studied.

Experimental demonstration of structural robustness of spatially partially coherent fields in turbulence.

Structured fields that are spatially completely coherent have been extensively studied in the context of long-distance optical communication, as the structure in the intensity profile of such fields is used for encoding information. This method of doing optical communication works very well in the absence of turbulence. However, in the presence of turbulence, the intensity structures of such fields start to degrade because of the complete spatial coherence of the field, and this structural degradation increases with the increase in turbulence strength.

Joint detection of claudin-1 and junctional adhesion molecule-A as a therapeutic target in oral epithelial dysplasia and oral squamous cell carcinoma.

Abnormal expression of claudin-1 (CLDN-1) and junctional adhesion molecule-A (JAM-A) has been described in certain malignancies but their clinical relevance is poorly understood. The present study aims to elucidate the role of CLDN-1 and JAM-A in oral epithelial dysplasia (OED) and oral squamous cell carcinoma (OSCC). Changes in the expression of these proteins were identified immunohistochemically on tissue sections from patients with OED and OSCC and compared with control.

Correlation of serum lactate dehydrogenase and alkaline phosphatase in different histological grades of head and neck squamous cell carcinoma and premalignant lesions.

Context: Head neck cancer (HNCA) in North-East India accounts for 54.48% cancers at all sites, one of the highest in the country. Increased serum lactate dehydrogenase (LDH) activity is considered as a marker of cellular necrosis while serum alkaline phosphatase (ALP) is recognized as an important marker of induction of tumor cell differentiation.

Clinical-radiological correlation and role of computed tomography staging in chronic rhinosinusitis.

Objective: This study aimed to determine whether there is a clinical-radiological correlation in chronic rhinosinusitis (CRS), to compare operative findings with those of computed tomography (CT) imaging, and to determine the importance of a CT score and staging in management of CRS.

Methods: This study is a prospective study. Adult patients meeting diagnostic criteria for CRS were prospectively studied using the Lund-Mackay (LM) symptom score and sinus CT scan.

BRCA1 and MDM2 as independent blood-based biomarkers of head and neck cancer.

We investigated the role of BRCA1, MDM2, and p53 in the pathogenesis of head and neck cancer (HNC) and evaluated their potential utility as blood-based predictive biomarkers of HNC. Immunostaining of tissue biopsies and whole blood lymphocytes (WBL) of 36 HNC patients were evaluated by immunohistochemistry (IHC) and immunocytochemistry (ICC), respectively. The staining intensities of BRCA1 and MDM2 in matched tissue and blood samples were significantly associated with cancer stage.

Nutritional Assessment of Patients with Head and Neck Cancer in North-East India and Dietary Intervention.

Introduction: Head and neck cancer (HNCA) patients have poor nutritional status which clearly bears a negative prognosis in cancer. There is no study and consensus on nutritional assessment tools and diet structure for such patients. This study intends to determine the prevalence of malnutrition and formulate a diet chart keeping in view the general food habit and economic condition of HNCA patients of North East (NE) region.

MDM2 and TP53 Polymorphisms as Predictive Markers for Head and Neck Cancer in Northeast Indian Population: Effect of Gene-Gene and Gene-Environment Interactions.

Background: Polymorphisms in the MDM2 309 (T>G) and TP53 72 (G>C) genes are reported to increase the susceptibility to head and neck cancer (HNC) in various populations. The risk for HNC is also strongly associated with etiologic habits such as smoking, alcohol consumption and/or chewing of betel quid (BQ). In a case-control study, we investigated the significance of the above polymorphisms alone, and upon interaction with one another as well as with various etiologic habits in determining HNC risk in a Northeast Indian population.

XPD, APE1, and MUTYH polymorphisms increase head and neck cancer risk: effect of gene-gene and gene-environment interactions.

In the present study, we investigated the effect of the DNA repair gene polymorphisms XPD Asp312Asn (G>A), APE1 Asp148Glu (T>G), and MUTYH Tyr165Cys (G>A) on the risk for head and neck cancer (HNC) in association with tobacco use in a population of Northeast India. The study subjects comprised of 80 HNC patients and 92 healthy controls. Genotyping was performed using amplification refractory mutation system-PCR (ARMS-PCR) for XPD Asp312Asn (G>A) and PCR using confronting two-pair primers (PCR-CTPP) for APE1 Asp148Glu (T>G) and MUTYH Tyr165Cys (G>A).

Frontoethmoidal encephalomeningocoele with colpocephaly: case report and clinical review.

Frontoethmoidal encephalomeningocoele is a rare congenital disease in which an intracranial mass protrudes through a midline defect from the anterior cranial fossa into the facial skeleton. The condition affects patients in South East Asian countries, such as Thailand, Burma, Malaysia and Indonesia, with frequency of 1 in 5000. The pathogenesis of encephalocoeles may be regarded as a 'late' neurulation defect during the fourth gestational week.

Prevalence of head and neck cancers in the north east-An institutional study.

In India, head and neck cancers (HNCA) account for 30-40% cancers at all sites. In North-eastern India, where this study was conducted, tobacco related oral cancer is very common which may be due to widespread habit of chewing tobacco. The lack of any study in this regard and alarmingly high prevalence of cancers of head and neck in this part of India has prompted us to take up this study.

Deviated nasal septum in the newborn-A 1-year study.

A prospective study of 200 newborn babies was done at Silchar Medical College Hospital from September 2002 to August 2003. The babies aged from 0 to 4 days were taken in the study. They were examined for any signs of nasal obstruction, birth trauma, prolonged labour, mode of delivery (forceps/vaginal/caeserian section), intrauterine malposition, postmaturity, birthweight, cephalopelvic disproportion, parity of the mother and gestational period.