Sexual Dimorphism and Susceptibility to Alzheimer's Disease: Understanding genetic involvement and other risk Factors.

Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by persistent cognitive decli ne, tau-containing intracellular neurofibrillary tangles, and β-amyloid (Aβ)-containing extracellular plaques. Early symptoms include patchy memory loss and some behavioural abnormalities. There is a plethora of studies that have reported sexual dimorphism and a higher prevalence of Alzheimer's disease in women.

Impact of sexuality on degenerative diseases.

Human sexuality is shaped by a complex interplay of biological, psychological, social, and cultural factors, influencing individual identity, behaviors, relationships, and sexual experience. Far from merely reflecting anatomical characteristics, sexuality encompasses emotional and sexual attraction toward individuals across gender spectrums, guided by factors including hormones, genetics, brain processes, and environmental influences. Societal norms and cultural beliefs also mold sexual expression, with diverse sexual identities being either embraced or stigmatized, impacting individual well-being.