Young Adults with Ischemic Stroke in Argentina: A National Multicenter Retrospective Registry Analysis (JACARANDA).

Background: Young adults account for up to 15% of all ischemic strokes, yet data from Latin America remain scarce. Understanding their clinical profile and outcomes is essential to inform targeted interventions and public health strategies. We aimed to characterize demographics, vascular risk factors, stroke etiology, access to acute reperfusion therapies, and 90-day outcomes in Argentine patients aged 18-50 years with ischemic stroke.

Metabolomic-based aging clocks.

Molecular aging clocks estimate biological age from molecular biomarkers and often outperform chronological age in predicting health outcomes. Types include epigenetic, transcriptomic, proteomic, and metabolomic clocks. NMR-based metabolomic clocks provide a non-invasive, high-throughput platform to assess metabolic health.

Antimicrobial resistance in Escherichia coli isolates from dairy farms (Santa Fe province, Argentina).

Antimicrobial resistance (AMR) poses a significant global threat, with E. coli serving as an indicator for resistance patterns in pathogens. This study evaluated the prevalence of AMR in E.

Mercury Isotope Variability in Pyrenean Lake Sediments during the Late Holocene: Sources, Deposition, and Environmental Controls.

Atmospheric mercury (Hg) emissions represent a persistent global threat to ecosystems and human health. Stable Hg isotopes have emerged as powerful tools to trace historical pollution sources and reconstruct depositional pathways in natural archives. In this study, we present a 4000-year reconstruction of Hg isotopic composition from two Pyrenean lake sediment records (Lake Marboré and Lake Estanya) located along an altitudinal gradient and compare them with those of a nearby ombrotrophic peatland (Estibere mire).