Publications by authors named "A Robin Temming"
Staphylococcus aureus (S. aureus) is one of the major causes of bovine mastitis, a disease with detrimental effects on health and wellbeing. Current control measures are costly, laborious and not always effective in eradicating S.
View Article and Find Full Text PDFTracing growth patterns in cod ( L.) using bioenergetic modelling.
Ecol Evol
November 2023
Understanding individual growth in commercially exploited fish populations is key to successful stock assessment and informed ecosystem-based fisheries management. Traditionally, growth rates in marine fish are estimated using otolith age-readings in combination with age-length relationships from field samples, or tag-recapture field experiments. However, for some species, otolith-based approaches have been proven unreliable and tag-recapture experiments suffer from high working effort and costs as well as low recapture rates.
View Article and Find Full Text PDFFetal and neonatal alloimmune thrombocytopenia (FNAIT) can occur due to maternal IgG antibodies targeting platelet antigens, causing life-threatening bleeding in the neonate. However, the disease manifests itself in only a fraction of pregnancies, most commonly with anti-HPA-1a antibodies. We found that in particular, the core fucosylation in the IgG-Fc tail is highly variable in anti-HPA-1a IgG, which strongly influences the binding to leukocyte IgG-Fc receptors IIIa/b (FcγRIIIa/b).
View Article and Find Full Text PDFAntibody Recognition of Different Wall Teichoic Acid Glycoforms.
ACS Cent Sci
October 2022
Article Synopsis
- Wall teichoic acids (WTAs) are essential components on Gram-positive bacteria surfaces and are being researched as potential targets for antibody treatments against infections, including MRSA.
- A variety of techniques were used to study synthetic WTA fragments and their interactions with monoclonal antibodies (mAbs 4461 and 4497), revealing key structural features necessary for antibody recognition and specificity.
- The research highlights the importance of both sugar modifications and phosphate groups in WTAs for antibody binding, shedding light on the mechanisms of cross-reactivity and the flexibility of the WTA structure in facilitating effective binding to antibodies.
Objectives: Understanding of lifelong control of disease processes associated with caries and its management is an essential part of dental education. This study evaluated the dental students' knowledge of caries diagnosis and management using the International Caries Classification and Management System (ICCMS).
Methods: A survey was conducted among undergraduate dental students at two dental schools, attending the sixth (centre 1) and seventh semester (centre 2), respectively.