Publications by authors named "A Percot"
Rare disorders related to tight junction (TJ) proteins have been associated with amelogenesis imperfecta. Pathogenic variants of , encoding claudin-10b, a cation transport pore, cause the autosomal recessive HELIX syndrome (Hypohidrosis, Electrolyte imbalance, hypoLacrymia, Ichthyosis, Xerostomia). Patients exhibit salivary dysfunction and rapid enamel wear after tooth eruption.
View Article and Find Full Text PDFRaman spectroscopy is a non-destructive analytical technique for characterizing organic and inorganic materials with spatial resolution in the micrometer range. This makes it a method of choice for space-mission sample characterization, whether on return or in situ. To enhance its sensitivity, we use signal amplification via interaction with plasmonic silver-based colloids, which corresponds to surface-enhanced Raman scattering (SERS).
View Article and Find Full Text PDFNew insights into the surface Enhanced Raman Scattering (SERS) response of adenine using chemometrics.
Spectrochim Acta A Mol Biomol Spectrosc
June 2024
The SERS response of adenine is one of the most studied, due to its outstanding exaltation. However, the spectra obtained strongly differ according to the experimental conditions and still remain not well understood. To be able to search for the presence of this molecule in complex environments, it is essential to better understand the SERS response of adenine alone.
View Article and Find Full Text PDFThe revalorization of incompatible polymer blends is a key obstacle in realizing a circular economy in the plastics industry. Polyolefin waste is particularly challenging because it is difficult to sort into its constituent components. Untreated blends of polyethylene and polypropylene typically exhibit poor mechanical properties that are suitable only for low-value applications.
View Article and Find Full Text PDFImpact of claudin-10 deficiency on amelogenesis: Lesson from a HELIX tooth.
Ann N Y Acad Sci
October 2022
Article Synopsis
- Claudin proteins are key players in tight junctions of epithelial tissues, affecting ion permeability, and mutations in CLDN10 lead to HELIX syndrome, which results in severe enamel wear among other symptoms.
- Research on a third molar from a HELIX patient showed that the enamel's structure and formation were normal, but revealed unusual variations in strontium levels in the enamel and dentin.
- The findings suggest that the enamel wear is likely linked to xerostomia rather than an inherent fragility of the enamel itself, although the strontium variations may indicate possible issues with renal function that need further study.