Clinical validation of the nursing diagnosis of inadequate nutritional intake in children with cancer.

Purpose: To clinically validate the nursing diagnosis "Inadequate Nutritional Intake" based on elements identified within a specific situation theory framework in the context of children with cancer.

Methods: This is a diagnostic accuracy study following the Standards for Reporting Diagnostic Accuracy Studies (STARD) protocol. Specifically, it refers to the clinical validation phase of the nursing diagnosis Inadequate nutritional intake, using a cross-sectional design.

Hyperglycemia and ZIKV infection cause physiological, immune, and oxidative testicular dysregulation.

In Brief: Chronic hyperglycemia prolongs ZIKV infection and exacerbates testicular damage in mice. The combined condition severely impairs spermatogenesis through oxidative stress and inflammation.

Abstract: Diabetes mellitus (DM) is among the leading causes of morbidity and mortality, with a rapid increase in its prevalence worldwide, particularly in developing countries.

Mixtures of phenolic extracts of , and fruits and identification of the anthocyanins by HPLC-DAD-ESI/MS.

A blend of phenolic extracts from jabuticaba (), jussara (), and blueberry () has been proposed as a viable approach for incorporating bioactive compounds into food products. In this study, concentrated phenolic extracts from these three fruits were combined to formulate a mixture with a high content of phenolic compounds, total anthocyanins, and antioxidant capacity. The anthocyanins profile of the fruits was analyzed by HPLC/MS.

Bifidobacteria and Celiac Disease: Mechanisms of Probiotic Action in Reducing Gluten-Induced Cytotoxicity and Inflammation.

Celiac disease (CD) is an immune-mediated systemic disorder triggered by gluten peptides present in the diets of genetically susceptible individuals, leading to a range of intestinal and extra-intestinal manifestations. Although managed by a gluten-free diet (GFD), symptoms persist in 30%-50% of treated individuals despite apparent dietary compliance. Accordingly, the present review explores how bifidobacteria may mediate cytotoxic and proinflammatory responses induced by gluten-derived peptides, contributing to the modulation of CD symptoms.

Molecular design drives nanoarchitecture in self-assembling antimicrobial peptides.

Antimicrobial peptides (AMPs) have emerged as promising alternatives owing to their broad-spectrum activity and reduced potential for resistance. Recent advances have highlighted the role of peptide self-assembly in enhancing the stability, bioavailability, and efficacy of AMPs. Through non-covalent interactions, self-assembly enables the formation of nanostructures, including nanofibers, nanotubes, and micelles.