Cervical cancer remains the leading cause of cancer death among women in sub-Saharan Africa and is more severe in high HIV-burdened countries due to persistent high-risk human papillomavirus (hrHPV). In 2021, the World Health Organization recommended primary hrHPV testing for cervical cancer screening; however, optimal triage strategies following positive hrHPV tests remain unclear. We conducted a prospective cost analysis of triage methods for positive hrHPV results among women living with and without HIV in Gaborone, Botswana.
View Article and Find Full Text PDFObjective: This study aimed to evaluate maternal outcomes in a large cohort with high prevalence of human immunodeficiency virus (HIV) infection in Botswana after implementation of a treat-all policy.
Methods: In this retrospective cohort study, data were collected from the medical record at the time of discharge from November 2021 to December 2023. Outcomes were recorded in the Tsepamo Birth Outcomes Surveillance and Safe Birth studies at Princess Marina Hospital in Botswana.
Organ transplant listing decisions are made by multidisciplinary selection committees using structured, deliberative processes to evaluate candidate eligibility. Engaging patients in these meetings has been proposed as a strategy to enhance transparency, trust, and patient-centered care. This study assessed patient and professional perspectives via an online survey of 1,349 American Society of Transplantation (AST) and National Kidney Foundation (NKF) members (907 patients, caregivers, family; 442 transplant team members).
View Article and Find Full Text PDFBackground: Effective communication of uncertain prognoses is a critical skill in obstetrics. Yet few curricula exist to prepare graduate medical education trainees for these high-stakes conversations.
Objective: To design and evaluate a multimodal curriculum for improving obstetric trainees' communication skills when conveying uncertain prognoses.
Ultrasound Obstet Gynecol
August 2025
Objective: The aim of the present study was to describe the diagnosis, management and outcomes of patients with prenatally diagnosed vasa previa (VP) at a single center in which routine VP screening is performed.
Methods: We carried out a retrospective cohort study of all patients with prenatally diagnosed VP at our institution (Beth Israel Deaconess Medical Center, Boston, MA, USA) between January 2010 and October 2024. We routinely screen all patients at the second-trimester anatomy scan by transabdominal ultrasound identification of the placental cord insertion and a color flow Doppler sweep over the cervix.