Cost-Effectiveness of Bempedoic Acid in High Cardiovascular Risk Patients with Statin Intolerance: An Analysis of the CLEAR Outcomes Trial.

Background: In the CLEAR Outcomes study, 13,970 high cardiovascular risk patients with hypercholesterolemia and statin intolerance were randomized to treatment with bempedoic acid or standard of care (placebo). Bempedoic acid reduced the risk of major adverse cardiovascular events by 13%. However, the cost-effectiveness of bempedoic acid in this patient population is unknown.

Coronary Stent Infection in Acute Double Valve Endocarditis.

We present a patient with aortic and mitral valve endocarditis who presented with acute ST-segment elevation myocardial infarction. The patient underwent percutaneous coronary intervention, aspiration thrombectomy, and stent placement. A transthoracic echocardiogram subsequently revealed endocarditis.