Prediction of long-term outcome by duration of the psychosis prodrome: Mixed effects models reveal continuity across 7 years but variation across quartile splits.

While associations between duration of untreated psychosis (DUP) and outcome are robust and have been influential in early intervention, whether similar associations and potential utility exist for the preceding duration of the psychosis prodrome (DPP) remain to be clarified. This study investigated prospectively across seven years: (i) whether DPP is associated with outcome; (ii) whether any prediction by DPP varies across long-term follow-up after initiating treatment; and (iii) whether these relationships vary across gradations of DPP values. Sixty subjects were evaluated for DPP at first episode psychosis (FEP) and for psychopathology and quality of life at both FEP and 7-year follow-up; functionality and service engagement were assessed at follow-up.

Ambulatory care by on-call teams in an Emergency Department.

Aim: Admission rate is a key performance indicator for Emergency Departments (EDs). Senior hospital management advised that, if discharge by on-call teams was possible within 24 hours, a patient should be termed 'ambulatory' and remain in the ED under the care of the on-call team rather than being admitted to a ward. This study aimed to assess the impact of this initiative on ED admission rates and occupancy.

Observations of a splitting ocean cyclone resulting in subduction of surface waters.

Earth's oceans contain large numbers of cyclonic eddies, 10 to 25 kilometers in diameter and unresolved in climate simulations. However, we lack observations of these features due to their small size and fast evolution. Here, we present in situ observations of one such cyclonic eddy with intense chlorophyll at its center as it spontaneously splits into two smaller cyclonic eddies over a few days.

Response Allocation of Board-Certified Behavior Analysts toward Categories of Evidence-Based Practice.

Board certified behavior analysts (BCBAs) are often called upon to recommend treatments while working with autistic individuals. As practitioners of the science of human behavior, behavior analysts must make recommendations supported by scientific evidence. However, at times, individual practitioners may inadvertently recommend interventions that are not evidence-based.