Multiscale Analysis Reveals Altered Characteristics in Femur and Mandible of Mice on a High Phosphate Diet.

Excessive phosphate used as flavor enhancers and preservatives in processed foods can exacerbate cardiovascular and kidney diseases. In clinical and pre-clinical studies, chronic (over 52 weeks) high-phosphate diet (HPD) negatively affects bone health. We previously demonstrated that 12-week-HPD decreases exercise capacity and skeletal muscle metabolism in adult male mice; however, alteration of bone characteristics associated with HPD independent of disease complications is not well-characterized.

Child-specific thoracic gas volume prediction equations for air-displacement plethysmography.

Objective: To develop child-specific thoracic gas volume (TGV) prediction equations for use in air-displacement plethysmography in 6- to 17-year-old children.

Research Methods And Procedures: Study 1 developed TGV prediction equations using anthropometric variables after completing a measured TGV and air-displacement plethysmography test in 224 healthy boys and girls (11.2 +/- 3.

Bone morphogenetic protein-7 selectively enhances mechanically induced bone formation.

The responses of bone cells to skeletal loading are clearly an important factor in bone biology, but much remains to be learned about the role of these responses in skeletal development, maintenance, and tissue repair. Bone morphogenetic proteins (BMPs) are key regulators of bone formation. We examined the effect of BMP-7 on periosteal and endosteal bone formation in response to increased mechanical loading using the rat tibial bending model.