Predictors of long-term survival in patients with a first episode of acute heart failure.

Introduction: Acute heart failure (AHF) represents a critical event in heart failure progression, yet data on long-term outcomes after first hospitalization, remain scarce. The aim is to describe long-term survival and evaluate its predictors after the first episode of AHF.

Material And Methods: Patients from five Spanish hospitals with a confirmed first diagnosis of AHF were categorized based on survival (≥5 or RESULTS: A total of 1986 patients were included, median age 76 years (range: 68-82), 50% women, and 57% with preserved LVEF.

Clinical-epidemiological aspects, hospitalization, and reconsultations in older patients with atrial fibrillation in emergency departments in Spain (EDEN-35 study): sex-disaggregated analysis.

Objective: To assess, from a sex/gender perspective, the incidence bof atrial fibrillation (AF) in older patients in Spanish hospital emergency departments (EDs), their clinical characteristics, need for hospitalization, short-term follow-up consultations, long-term readmissions and mortality, and associated factors.

Methods: We included all patients aged $ 65 years diagnosed with AF in 52 Spanish EDs over a 1-week period. The outcome variables were the need for hospitalization, all-cause follow-up consultations within 30 days following discharge, and long-term readmissions and mortality.

Carbohydrate antigen 125 determined on arrival at the emergency department correlates with severity of decompensation and adverse outcomes in patients with acute heart failure.

To investigate the capacity of carbohydrate antigen 125 (CA125) to detect severe decompensation in patients diagnosed with acute heart failure (AHF) in the emergency department (ED) and to predict 1-year mortality. We assessed CA125 at ED arrival in unselected patients diagnosed with AHF in five Spanish hospitals during November-December 2022. CA125 was categorized as tertiles.

Factors associated with the use of sodium-glucose cotransporter 2 (SGLT2) inhibitors after an episode of acute heart failure and prognostic impact.

Objectives: To analyze the factors associated with the use of sodium-glucose cotransporter 2 inhibitors (SGLT2i) and the association between use SGLT2i and post discharge adverse clinical endpoints (composite of 30-day visit to emergency department or acute heart failure -AHF- readmission or death) and 1-year mortality.

Methods: We included all patients diagnosed with AHF in 40 Spanish emergency departments (ED) in November-December 2022 with available data on chronic treatment and at discharge and grouped them according to whether they received iSGLT2 at discharge. Treatment with SGLT2i was categorized in never user, prior use and initiation during decompensation.

Identification of phenotypes in heart failure with preserved ejection fraction among 8161 patients from 3 Spanish cohorts.

Introduction And Objectives: To identify phenotypes in heart failure with preserved ejection fraction (HFpEF), compare mortality, and investigate whether treatments have different effects according to phenotype.

Methods: We performed a secondary analysis of 8161 patients with HFpEF included in Spanish cardiology (INCLIVA), internal medicine (RICA), and emergency (EAHFE) registries. Phenotypic clusters based on 16 baseline characteristics were identified using latent class analysis.