The IIIVmrMLM method uncovers new genetic variants associated with resistance to Fusarium wilt in flax.

Flax (Linum usitatissimum) is an important agricultural crop grown for fiber and oil production, playing a key role in various industries such as production of paints, linoleum, food, clothes and composite materials. Fusarium wilt caused by the fungus Fusarium oxysporum f. sp.

Chickpea diversity driven by transposon insertion polymorpism.

Chickpea is the second most important legume crop, which is used as a food by people in different parts of the world due to its high nutritive value. Omics technologies have revolutionized the characterization of chickpea genetic diversity by considering single-nucleotide polymorphisms, while structural variants and transposons have been overlooked. The specific contribution of transposons to the phenotypic diversification of crop species is still poorly documented, therefore its characterization is important.

Amyloid Fibrils of the s36 Protein Modulate the Morphogenesis of Eggshell.

is the oldest classic model object in developmental genetics. It may seem that various structures of the fruit fly at all developmental stages have been well studied and described. However, recently we have shown that some specialized structures of the eggshell contain an amyloid fibril network.

Sustained cancer-relevant alternative RNA splicing events driven by PRMT5 in high-risk neuroblastoma.

Protein arginine methyltransferase 5 (PRMT5) is over-expressed in a wide variety of cancers and is implicated as having a key oncogenic role, achieved in part through its control of the master transcription regulator E2F1. We investigated the relevance of PRMT5 and E2F1 in neuroblastoma (NB) and found that elevated expression of PRMT5 and E2F1 occurs in poor prognosis high-risk disease and correlates with an amplified Myelocytomatosis viral-related oncogene, neuroblastoma-derived (MYCN) gene. Our results show that MYCN drives the expression of splicing factor genes that, together with PRMT5 and E2F1, lead to a deregulated alternative RNA splicing programme that impedes apoptosis.

Pangenomics of flax fungal parasite f. sp. .

To assess the genomic diversity of f. sp. strains and compile a comprehensive gene repertoire, we constructed a pangenome using 13 isolates from four different clonal lineages, each exhibiting distinct levels of virulence.