Global, regional, and national burden of inflammatory bowel disease in persons aged 60-89 years from 1992 to 2021.

Background: The global burden of inflammatory bowel disease (IBD) is increasing, but detailed data on older adults remain scarce.

Objective: This study describes trends in incidence, prevalence, mortality, and disability-adjusted life years (DALYs) of IBD among individuals aged 60-89 years from 1992 to 2021 at global, regional, and national levels, and forecasts the epidemiological status for 2030.

Methods: We used the Global Burden of Disease (GBD) database, covering 204 countries and territories.

Efficacy and safety of dual versus mono antiplatelet therapy in patients with stroke or transient ischemic attack: An updated meta-analysis of 18 randomized controlled trials.

The optimal duration of dual antiplatelet therapy (DAPT) as a routine treatment in stroke patients is still controversial. The efficacy and safety of DAPT may vary with different regiments, initiating treatment time and race. Our study assessed the efficacy and safety of DAPT in patients with stroke and to determine the factors influencing the efficacy and safety of DAPT.