2 results match your criteria: "Iran. Electronic address: Baharvand@Royaninstitute.org.[Affiliation]"

Effects of Alginate Concentration and Ovarian Cells on In Vitro Development of Mouse Preantral Follicles: A Factorial Study.

Int J Fertil Steril

January 2020

Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.Electronic address:

Article Synopsis
  • The study assessed how different concentrations of alginate hydrogels and the presence of ovarian cells affect follicle development in mice.
  • In cultures with 0.5% alginate, preantral follicles showed better survival rates compared to higher concentrations, while 1% alginate promoted more antrum formation and reduced oocyte degeneration.
  • Co-culturing with ovarian cells enhanced follicle growth, survival, and hormone production, leading to improved oocyte quality.
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Metabolic Signature of Pluripotent Stem Cells.

Cell J

October 2018

Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.

Objective: Pluripotent stem cells (PSCs), with the capacity to self-renew and differentiate into all other cell types, are of benefit in regenerative medicine applications. Tightly controlled gene expression networks and epigenetic factors regulate these properties. In this study, we aim to evaluate the metabolic signature of pluripotency under 2i and R2i culture conditions versus serum condition.

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