The pharmacokinetic characteristics of sulfadiazine in channel catfish (Ictalurus punctatus) following oral and intravenous administrations.

This study aimed to determine the bioavailability and pharmacokinetic parameters of sulfadiazine (SDZ) in channel catfish (Ictalurus punctatus) following oral gavage and intravenous injection. The healthy channel catfish were orally and intravenously administrated with SDZ solution at doses of 50 and 5 mg/kg, respectively. Plasma samples were determined by ultra-performance liquid chromatography with an ultraviolet detector.

Geographic Authentication of Leaves Using Multivariate Analysis and Preliminary Study on the Compositional Response to Environment.

To explore the influences of different cultivated areas on the chemical profiles of leaves (EUL) and rapidly authenticate its geographical origins, 187 samples from 13 provinces in China were systematically investigated using three data fusion strategies (low, mid, and high level) combined with two discrimination model algorithms (partial least squares discrimination analysis; random forest, RF). RF models constructed by high-level data fusion with different modes of different spectral data (Fourier transform near-infrared spectrum and attenuated total reflection Fourier transform mid-infrared spectrum) were most suitable for identifying EULs from different geographical origins. The accuracy rates of calibration and validation set were 92.

Tissue residue depletion kinetics and withdrawal time estimation of doxycycline in grass carp, Ctenopharyngodon idella, following multiple oral administrations.

This study aimed to determine the plasma and tissue residue depletion kinetics of doxycycline (DC) in grass carp (Ctenopharyngodon idella) after daily oral administrations at 20 mg/kg for 3 days, and to calculate the corresponding withdrawal times. Following drug administrations, samples of plasma, liver, kidney, gill and muscle + skin were collected at predetermined time points (0.25, 0.

Ethnobotany, Phytochemistry and Pharmacological Properties of Eucommia ulmoides: A Review.

Eucommia ulmoides Oliver, a single species of Eucommia genus belonging to the Eucommiaceae family, is an endemic in China and has been used in traditional Chinese medicine for nearly two thousand years. Records from different historical periods highlight E. ulmoides and its officinal botanical parts, usefulness in adaptation to disease and its central role in Chinese medicine theory.