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Climate change may lead to increased or decreased future forest productivity. However, more frequent storms are expected in Europe and are increasingly considered an important abiotic damage factor for forests, leading to windthrows that result in both economic and ecological losses. Remote sensing data helps in detecting past windthrow and assessing both ecological and economic losses. In this study, carried out in Bolu Regional Forest Directorate (RFD), the windthrow areas between 2017 and 2019 were detected by using the Normalized Difference Fraction Index (NDFI) from the Sentinel-2A satellite image of Google Earth Engine Platform (GEE). The MaxEnt method was used to ascertain the relationship between windthrow damage and environmental variables. Wind speed, stand type (pure/mixed), precipitation, texture, distance to road, elevation, root types, slope (degree), and site index were used as environmental variables in the modeling. The value of the area under the curve (AUC) of the model was determined to be 0.821. According to the modeling results, the environmental variables that have the greatest impact on windthrow damage are site index and wind speed. In areas with a site index of '1' and wind speeds between 35-42 km/h and 53-65 km/h, it has been determined that there is an increased risk of windthrow. This study will enable forest managers to make ecological assessments to reduce the occurrence of windthrow. As a result of ecological assessments, it is anticipated that improvements in forest management planning will lead to a reduction in disturbances caused by windthrow.
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http://dx.doi.org/10.1007/s10661-025-14529-x | DOI Listing |
Haematologica
September 2025
Division of Medical Oncology, University Hospital Basel, Basel, Switzerland; Laboratory of Translational Immuno-Oncology, Department of Biomedicine, University and University Hospital Basel, Basel.
We previously used a disease-specific B cell receptor (BCR) point mutation (IGLV3-21R110) for selective targeting of a high-risk subset of chronic lymphocytic leukemia (CLL) with chimeric antigen receptor (CAR) T cells. Since CLL is a disease of the elderly and a significant fraction of patients is not able to physically tolerate CAR T cell treatment, we explored bispecific antibodies as an alternative for precision targeting of this tumor mutation. Heterodimeric IgG1-based antibodies consisting of a fragment crystallizable region (Fc) attached to both an anti-IGLV3-21R110 Fab and an anti-CD3 (UCHT1) single chain variable fragment (R110-bsAb) selectively killed cell lines engineered to express high levels of the neoepitope as well as primary CLL cells using healthy donor and CLL patient-derived T cells as effectors.
View Article and Find Full Text PDFPlant Genome
September 2025
Department of Agronomy, Iowa State University, Ames, Iowa, USA.
Crop growth rate is a critical physiological trait for forage and bioenergy crops like sorghum [Sorghum bicolor (L.) Moench], influencing overall crop productivity, particularly in photoperiod-sensitive (PS) types. Crop growth rate studies focus on either a physiological approach utilizing a few genotypes to analyze biomass accumulation or a genetic approach characterizing easily scorable proxy traits in larger populations.
View Article and Find Full Text PDFBiotechnol J
September 2025
Department of Molecular Biosciences and Bioengineering, University of Hawai'i at Mānoa, Honolulu, Hawai'i, USA.
CRISPR technologies are rapidly transforming agriculture by enabling precise and programmable modifications across a wide range of organisms. This review provides an overview of CRISPR applications in crops, livestock, aquaculture, and microbial systems, highlighting key advances in sustainable agriculture. In crops, CRISPR has accelerated the improvement of traits such as drought tolerance, nutrient efficiency, and pathogen resistance.
View Article and Find Full Text PDFNurs Open
September 2025
Doctoral School of Health Sciences, Faculty of Health Sciences, University of Pécs, Pécs, Hungary.
Aims: To find out how Kenyan nurses rate their organisational culture, determine their level of job satisfaction, and organisational culture predictors of job satisfaction.
Design: A cross-sectional online survey.
Methodology: A total of 300 nurses across Kenya were invited to participate in this study.
NPJ Biofilms Microbiomes
September 2025
Imperial College Parturition Research Group, Institute of Reproductive and Developmental Biology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
The mechanisms by which vaginal microbiota shape spontaneous preterm birth (sPTB) risk remain poorly defined. Using electronic clinical records data from 74,913 maternities in conjunction with metaxanomic (n = 596) and immune profiling (n = 314) data, we show that the B blood group phenotype associates with increased risk of sPTB and adverse vaginal microbiota composition. The O blood group associates with sPTB in women who have a combination of a previous history of sPTB, an adverse vaginal microbial composition and pro-inflammatory cervicovaginal milieu.
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