Synopsis of recent research by authors named "Zengrong Xiao"
- Zengrong Xiao's research primarily investigates the role of long noncoding RNAs (lncRNAs) in regulating pluripotency and differentiation in human and mouse stem cells, revealing how specific lncRNAs can influence cellular states and development.
- In a 2019 study, Xiao identified that the knockdown of lncRNA CCDC144NL-AS1 promotes conversion to a naïve-like state in human pluripotent stem cells, highlighting its significance in pluripotency regulation that could advance regenerative medicine.
- Additionally, Xiao's 2018 research introduced lnc158, an endogenous antisense transcript of nuclear factor-IB (NFIB), which plays a crucial role in the differentiation of mouse neural precursor cells into oligodendrocytes, contributing to our understanding of oligodendrocyte maturation processes.