For gay, bisexual, and other sexual minority men (SMM), geo-social exposures in residential and non-residential places are important to consider for health, as home, social, sexual, substance use, and healthcare-related locations may be different. We use survey data from a sample of 219 Black and Hispanic SMM within Los Angeles County to examine the places that individuals visit for eight specific activities, categorized as either lifestyle or healthcare-related. Spatial clustering techniques are used to identify hotspots, or places where individual's activities are clustered in space, for each activity.
View Article and Find Full Text PDFSin Nombre virus (SNV) is the main causative agent of hantavirus cardiopulmonary syndrome (HCPS) in North America. SNV is transmitted via environmental biological aerosols (bioaerosols) produced by infected deer mice (). It is similar to other viruses that have environmental transmission routes rather than a person-to-person transmission route, such as avian influenza (e.
View Article and Find Full Text PDFPurpose: Circulating tumor cells (CTCs) are biomarkers associated with poor prognosis and treatment resistance in hormone receptor-positive (HR+)/HER2-negative metastatic breast cancer (MBC). This analysis evaluates the prognostic role of baseline CTC enumeration and its interaction with treatment regimens in patients progressing on CDK4/6 inhibitors.
Experimental Design: The PACE trial is a phase II, multicenter, randomized study of HR+/HER2- MBC patients experiencing progression on aromatase inhibitors (AI) and CDK4/6 inhibitors.
Prior studies of halobenzene-ammonia complexes have shown that the nature of the cationic intermediate (i.e., Wheland-type vs ion-radical) may play a key role in determining the reaction products.
View Article and Find Full Text PDFPurpose: Children with neurodevelopmental disorders often experience difficulties in acquiring and executing movement skills. Although the motor profiles of neurodivergent children frequently overlap, rigid conceptual distinctions between diagnostic labels have been imposed by traditional categorical approaches to taxonomy. An alternative transdiagnostic approach is proposed to better represent the similarities between presentations.
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