Divergent coupling of -alkynylnaphthols and -quinone monoketals through a Michael addition/intramolecular annulation cascade to access benzofuryl β-naphthols.

A CFOH-catalysed tandem cyclization of -alkynylnaphthols and -quinone monoketals is disclosed. The CFOH catalyst activates alkynylnaphthol to generate an all-carbon tetrasubstituted VQM by nucleophilic addition to quinone monoketal (Michael addition). Furthermore, the CFOH catalyst triggers -quinone monoketal to generate an electrophilic oxocarbenium cation to be captured by -alkynylnaphthol regiospecifically, resulting in the formation of an all-carbon tetrasubstituted VQM, followed by an intramolecular cyclization to afford a series of 1-(3-arylbenzofuran-2-yl)naphthalen-2-ols.

First Measurement of ν_{e} and ν[over ¯]_{e} Charged-Current Single Charged-Pion Production Differential Cross Sections on Argon Using the MicroBooNE Detector.

Understanding electron neutrino interactions is crucial for measurements of neutrino oscillations and searches for new physics in neutrino experiments. We present the first measurement of the flux-averaged ν_{e}+ν[over ¯]_{e} charged-current single charged-pion production cross section on argon using the MicroBooNE detector and data from the NuMI neutrino beam. The total cross section is measured to be [0.

Yogic Breathing as a Modality to Reduce Stress in Anesthesia Professionals as Measured by Hair Cortisol: A Feasibility Study.

Many health care professionals are struggling to cope with high stress and burnout in the workplace. To support these professionals, several strategies have been proposed, including meditation and breathing exercises. This pilot study aimed to determine the feasibility of yogic breathing as a strategy for managing stress and burnout for anesthesia professionals.

An unnatural base pair for the detection of epigenetic cytosine modifications in DNA.

Natural, covalently modified cytosine bases within genomic DNA function as important epigenetic markers. Approaches for single-base-resolution sequencing of cytosine modifications typically deploy chemistry for modification-selective C-to-T code conversion and can require error-prone subtractive analysis of complex data. Here we report the sequencing of an epigenetic base by exploiting an unnatural base pair system.

Cancer Incidence and Mortality Across 43 Cancer Registries in India.

Importance: Cancer is a significant global health concern, with India ranking second in Asia and third in the world in terms of cancer incidence. Regular monitoring and updates on cancer statistics are vital for assessing the impact and burden of the disease and the effectiveness of cancer control measures.

Objective: To measure the recent patterns and trends in cancer incidence and mortality across 43 geographic regions in India from 2015 to 2019 and to provide estimates for 2024.