Evaluation of aetiological profiles, treatment appropriateness, and outcomes of syndromic management for reproductive tract infections in women from urban clinics.

Background While syndromic management is widely used in low-resource settings due to its cost-effectiveness and ease of patient care, growing concerns of antimicrobial resistance (AMR) and potential overtreatment highlight the need for regular aetiological testing to monitor treatment appropriateness. Aim To evaluate and compare syndromic management for reproductive tract infection for assessing treatment strategies. Methods In a prospective study, 250 sexually active, non-pregnant women aged 18-50 years, presenting with symptoms of lower genital tract infections were recruited as part of a prospective study from urban clinics in Mumbai.

Indications and Technique for Thoracic Segmental Spinal Anesthesia in Clinical Practice: A Narrative Review.

Thoracic segmental spinal anesthesia (TSSA) represents an advanced technique in present clinical anesthetic practice. By lowering the systemic effects of anesthesia, preserving improved hemodynamic stability, and accelerating postoperative recovery, its targeted approach provides significant benefits in certain upper abdominal and thoracic procedures, particularly in high-risk patients. However, careful patient selection, exact technical execution, and in-depth understanding of thoracic anatomy are necessary for its successful implementation.

Variations in Creatinine Generation Among Patients With Glomerular Disease: Evidence From the NEPTUNE and CureGN Studies.

Rationale & Objective: Estimation of glomerular filtration rate (GFR) assumes that creatinine generation (crG) is relatively stable. This study identified factors associated with crG variability and its impact on serum creatinine changes ( Scr) among patients with glomerular disease.

Study Design: An observational cohort study.