Predicting In-Hospital Cardiac Arrest Using Machine Learning Models: Protocol for a Scoping Review.

Background: In-hospital cardiac arrest (IHCA) remains a public health conundrum with high morbidity and mortality rates. While early identification of high-risk patients could enable preventive interventions and improve survival, evidence on the effectiveness of current prediction methods remains inconclusive. Limited research exists on patients' prearrest pathophysiological status and predictive and prognostic factors of IHCA, highlighting the need for a comprehensive synthesis of predictive methodologies.

Butein mitigates 5-FU-triggered hepatotoxicity via antioxidant, anti-inflammatory, and anti-apoptotic pathways.

5-Fluorouracil (5-FU) is a widely used chemotherapeutic agent, but its hepatotoxic potential poses clinical challenges, as it induces oxidative stress, inflammation, and apoptosis in liver tissue. Butein, a natural chalcone flavonoid that possesses varied biological activity, such as anticancer, anti-inflammatory, and antiplatelet effects. This study aimed to evaluate the possible protective effects of Butein against 5-FU-induced hepatotoxicity in rats.

Social devaluation and mental health among refugees in the Middle East.

Refugees who have experienced war and persecution often suffer from psychological disorders resulting from adverse events and living conditions. Current theories of traumatic stress focus on processes resulting from threats to physical integrity, with little consideration of social stressors. In this study, we proposed that perceptions of social devaluation, which include specific emotions, appraisals, physiological responses, and behavioural impulses associated with devaluation, partially mediate the relationship between stress and psychological symptoms in refugees.

A Case of Recurrent Dermatofibrosarcoma Protuberans With Fibrosarcomatous Transformation.

Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue sarcoma with a generally low risk for metastasis. Most individuals are diagnosed with this neoplasm in the third or fourth decade of life, with the growth usually being no larger than 5 cm in maximum diameter at the time of diagnosis. The majority of these patients are treated with wide local excision, with most experiencing no recurrence or metastasis.

Quality of life among epileptic patients in Khartoum State neurological clinics, Sudan: a cross-sectional study.

Background: Epilepsy is a chronic non-communicable disease defined as recurrent and unprovoked seizures. Epilepsy causes a wide range of challenges that affect the patient's quality of life (QoL). This study aimed to assess the quality of life and associated factors among patients with epilepsy in Khartoum State, Sudan.