Evaluation of Atypical FISH Findings by RNA Sequencing.

Fluorescence in situ hybridization (FISH) utilizing a break-apart probe (BAP) design is a rapid, clinically useful method for targeted evaluation of gene rearrangements in formalin-fixed, paraffin-embedded (FFPE) tumors. While clinically validated BAP FISH assays usually yield unequivocal positive or negative results, rare tumors yield equivocal FISH results. This study had two aims: 1) to summarize typical and atypical BAP FISH results on 56,584 FFPE solid tumors over approximately one decade of clinical testing, and 2) to investigate the clinical utility of RNA-seq for tumors with equivocal FISH results.

Complications Following Laparoscopic Hysterectomy with Concomitant Appendectomy: A National Analysis.

Objective: To evaluate whether concomitant appendectomy during laparoscopic hysterectomy (LH) for benign indications is associated with increased short-term postoperative complications.

Design: This is a retrospective cohort study based on prospectively collected data.

Setting: American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database.

Registered Nurses and Meaningful Recognition: Contemporary Preferences of a Diverse Workforce.

Background: Meaningful recognition acknowledges the value of individuals' professional contributions to an organization's work. Long recognized as necessary to retain nurses, it includes formal awards programs, informal feedback processes, salary, and scheduling flexibility. With demographic characteristics of the nursing workforce changing, new research is needed to understand how contemporary nurses view meaningful recognition.

Correction: Wayland et al. Lenition in L2 Spanish: The Impact of Study Abroad on Phonological Acquisition. 2024, , 946.

In the original publication [...

The reference genome of a Sierra Nevada endemic, the cut-leaved monkeyflower, Mimulus laciniatus (syn. Erythranthe lacinata).

Mimulus laciniatus (syn. Erythranthe lacinata) is an annual plant endemic to the Sierra Nevada region of California. Mimulus laciniatus is notable for its specialized ecological niche, thriving in granite outcrops of alpine environments characterized by shallow soils that dry out rapidly as the snowpack is exhausted during season-ending droughts.