Using a patient-reported history questionnaire to aid decision-making in the lung cancer diagnostic pathway: a single centre observational study of primary care chest X-ray referrals.

Aim: To determine the utility and efficacy of a patient-reported history questionnaire to identify the presence of red flag symptoms indicative of lung cancer.

Materials And Methods: The study site introduced a paper-based screening questionnaire in 2019 to establish the presence of patient-reported red flag symptoms. This retrospective four-week (February 2020) single-centre observational study determined the prevalence of symptoms, compared referrer-reported to patient-reported clinical history, explored the relationship to the chest X-ray (CXR) outcome, and identified those diagnosed with lung cancer in the following two years.

Feasibility and Acceptability of Intervention and Trial Procedures of the UCL Live Well With Parkinson's Self-Management Toolkit.

Managing Parkinson's disease (PD) symptoms can be challenging due to multiple factors, including complex symptoms, which are often reported late, and a lack of resources, resulting in worse outcomes. Self-management of PD symptoms is a priority for patients, their carers, healthcare staff and systems. However, there is no effective comprehensive self-management intervention for use in the United Kingdom to support people with PD to self-manage problematic symptoms.

Evidence for deliberate burial of the dead by .

In this study, we describe new results of excavations in the Dinaledi Subsystem of the Rising Star cave system, South Africa. In two areas within the Hill Antechamber and the Dinaledi Chamber, this work uncovered concentrations of abundant fossils including articulated, matrix-supported skeletal regions consistent with rapid covering by sediment prior to the decomposition of soft tissue. We additionally re-examine the spatial positioning of skeletal material and associated sediments within the Puzzle Box area, from which abundant remains representing a minimum of six individuals were recovered in 2013 and 2014.

Ganglionated plexi ablation impact on AF mechanisms and outcomes in patients with low scar burden.

Background And Aims: Persistent atrial fibrillation (AF) ablation success rates remain limited. The aim was to evaluate the impact of ganglionated plexi (GP) ablation on AF mechanisms and outcomes in patients with low scar burden.

Methods: Patients undergoing persistent AF ablation were included.

Scottish and Newcastle Antiemetic Protocol (SNAP) 12-hour acetylcysteine regimen for paracetamol overdose reduces anaphylactoid reactions without compromising hepatic protection in all age groups: a secondary analysis.

Background: Treatment with the 12-hour Scottish and Newcastle Antiemetic Protocol (SNAP) acetylcysteine regimen is associated with decreased length of stay and fewer anaphylactoid reactions in adult patients, and the protocol is now recommended by several UK organisations and used widely. One potential barrier to adoption is concern regarding the potential for variation in protocol performance with patient age. Anecdotally, this has led to slower adoption in paediatric settings.