Effective detection of staphylococcal infections in human bone tissue using combined raman microscopy and micro-computed tomography.

Bone infections caused by and are serious complications in orthopedic surgery. These infections commonly occur in joint replacements, fracture management, and bone grafting procedures. Rapid and accurate pathogen-specific diagnostic methods are urgently needed to support early clinical decisions.

HR-pQCT and 3D Printing for Forensic and Orthopaedic Analysis of Gunshot-Induced Bone Damage.

Recent breakthroughs in three-dimensional (3D) printing and high-resolution imaging have opened up new possibilities in personalized medicine, surgical planning, and forensic reconstruction. This study breaks new ground by evaluating the integration of high-resolution peripheral quantitative computed tomography (HR-pQCT) with multimodal imaging and additive manufacturing to assess a chronic, infected gunshot injury in the knee joint of a red deer. This unique approach serves as a translational model for complex skeletal trauma.

Detection of bone infections using Vis-NIR and SWIR hyperspectral imaging coupled with machine learning.

Bone infections, such as fracture-related and periprosthetic joint infections, present significant diagnostic and therapeutic challenges in orthopaedic surgery. Current diagnosic standards rely primarily on tissue cultures of intraoperatively obtained samples - a time-consuming approach with limited sensitivity and specificity and delayed clinical decision-making. This study investigates the use of hyperspectral imaging (HSI) in the visible and near-infrared (Vis-NIR), and short-wave infrared (SWIR) spectral ranges for the rapid detection of bone infections.

The myth of 2.5 cm symphyseal diastasis.

Detection of disruption of the pubic symphysis and resulting anterior pelvic ring instability primarily depends on the symphyseal widening on standard anterior-posterior X-rays. Based on biomechanical and clinical analyses from the 80 to 90's, a cut-off value of 2.5 cm widening distinguished between stable and unstable lesions.

Helicopter vs. ground-based transfer for emergency interhospital transportation: A time and cost-efficiency analysis across varying transfer distances.

Background: Emergency interhospital transfer can be conducted using either ground-based emergency medical services (GEMS) or helicopter emergency medical services (HEMS). The choice between these modes of transportation relies mostly on urgency and transfer distances, however they are further influenced by road traffic, weather and resource availability. While some studies suggest that HEMS may improve survival rates for severely injured patients, the time efficiency of HEMS versus GEMS across varying distances remains underexplored.