Targeting Diabetic Complications through Oleuropein-Mediated Enzyme Modulation: A Chemical Biology Study in the Human-Relevant Model .

This study investigates the therapeutic potential of oleuropein-rich olive leaf extract (OLE) and pure oleuropein compound (OLC) in mitigating diabetes-induced organ damage using , a well-established model for metabolic syndrome. Despite the rising global burden of diabetes and associated complications, effective interventions targeting multiorgan dysfunction remain limited. Oleuropein, a polyphenolic compound with documented antioxidant and anti-inflammatory properties, was administered orally at 1 mg/kg body weight over 7 months to six experimental groups subjected to high- or low-calorie diets to simulate diabetic and control conditions.

Understanding Loneliness as a Preventive Health Priority Among Men: Findings From an Australian Population Survey.

Issue Addressed: Masculinity norms and risky behaviours are often identified as drivers of poorer health among men, and one underlying factor that is increasingly found to be important is loneliness. The aim of this study is to describe the prevalence of loneliness in Australian men and its relationship with preventive health capabilities.

Methods: A national cross-sectional survey of men aged 18 years and over (N = 1282) was conducted.

Combined effects of constant temperature and radio frequency exposure on Aedes mosquito development.

Mosquito-borne diseases, such as dengue, Zika, and chikungunya, pose significant public health threats, particularly in tropical regions like Malaysia. Aedes aegypti and Aedes albopictus are primary vectors of these diseases, with their developmental stages being highly sensitive to environmental factors. While temperature is a well-known driver of mosquito biology, the potential influence of anthropogenic factors such as radio frequency (RF) exposure remains underexplored.

Clinical and economic impact of digital dashboards on hospital inpatient care: a systematic review.

Objective: Digital dashboards are used to monitor patients and improve inpatient outcomes in hospital settings. A systematic review assessed the impact of dashboards across five outcomes of hospital mortality, hospital length of stay (LOS), economic impacts, harms, and patient and carer satisfaction.

Materials And Methods: Nine databases were searched from inception to May 2024.