A Preliminary Survey of Speech-Language Pathologists' Perceived Effectiveness and Challenges of Tele-Practice in India.

Introduction: Tele-practice in speech-language pathology has existed for nearly a decade, but it emerged as a solution to overcome the challenges of access issues in delivering speech-language pathology services globally, particularly during the COVID-19 pandemic. However, it is essential to follow up on tele-practice services following a pandemic concerning their efficacy and factors influencing their implementation as a routine or long-term service delivery method. This study investigated speech-language pathologists' perceived effectiveness and challenges of tele-practice in India.

Incident characterization of health conditions in women suspected of being victims of intimate partner violence.

Intimate partner violence (IPV) is a serious public health problem due to its severe health outcomes and its association with significant morbidity and mortality. There are many prevalence studies about this topic but few on incidence. Therefore, an incident health characterization of alleged IPV victims may be relevant to understanding the situation of the person at the moment when the suspicion of violence was recorded.

Implementing electronic health record-based anxiety and depression screening in an epilepsy clinic: Theory-based implementation strategy and pre-post quantitative outcomes using Reach, Effectiveness, Adoption, Implementation, and Maintenance.

Introduction: Anxiety and depression in epilepsy are common and impactful. Screening with validated measures at every epilepsy visit is a quality measure, yet screening remains limited due to time constraints.

Methods: This study aimed to develop an implementation strategy for anxiety and depression screening at an epilepsy center and evaluate it in a pre-post design with RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance).

Refined intake assessment of seven sweeteners via foods and beverages by the Dutch population using branded data.

The intake of seven sweeteners (acesulfame K, aspartame, cyclamates, saccharins, steviol glycosides, sucralose (all chronic intake) and erythritol (acute intake)) foods and beverages by the Dutch population was assessed in a refined assessment using branded data (product labels, use levels and consumption shares of brands) and scenarios for brand-loyalty. In general, the intake of these sweeteners was below their respective health-based guidance values (HBGVs). Only for toddlers high intakes of acesulfame K, cyclamates and erythritol were around or slightly above the HBGV in the most conservative scenario ('full brand-loyalty, consumers only').

Characterizing Monoclonal Antibody Aggregation Using Charge Detection Mass Spectrometry and Industry Standard Methods.

Protein aggregation is a factor in a multitude of neurodegenerative diseases and aggregates of protein-based biotherapeutics can cause toxicity and adverse patient outcomes. Monoclonal antibody (M)-fluorophore (F) complexes with four different antibody sequences and masses of ∼680 kDa were analyzed using size-exclusion chromatography (SEC) and mass spectrometry using both quadrupole-time-of-flight (QTOF) and charge detection mass spectrometry (CDMS). Higher-order aggregates were not resolved using SEC, but species as large as the MF complex and MF were resolved using QTOF and CDMS, respectively.