Comparative efficacy and safety of POLARx versus Arctic front advance pro cryoballoon systems for pulmonary vein isolation in atrial fibrillation: an updated systematic review and meta-analysis.

Background: Cryoballoon (CB) ablation is a well-established treatment for atrial fibrillation (AF). The Arctic Front Advance Pro™ (AFA-Pro) system, in use for over a decade, has demonstrated consistent efficacy and safety. Recently, the POLARx™, a novel CB system, has gained attention due to its advanced design and comparable clinical outcomes.

Frequency and Clinical Correlates of Thyroid Dysfunction in Patients With Type 2 Diabetes Mellitus: A Cross-Sectional Study.

Background: Thyroid dysfunction commonly coexists with type 2 diabetes mellitus (T2DM), compounding metabolic derangements and increasing the risk of complications. Despite its clinical significance, the prevalence and spectrum of thyroid dysfunction among South Asian patients with T2DM remain incompletely characterized. This study aimed to determine the frequency and types of thyroid dysfunction in patients with T2DM and to examine its associations with demographic characteristics, glycemic control, metabolic parameters, and microvascular complications.

Disparities in Anemia and Heart Failure-Related Deaths: Insights from a 23-Year National Analysis.

Background: Anemia and heart failure (HF) often coexist, contributing to increased morbidity and mortality. This study analyzed mortality trends linked to anemia and HF in U.S.

Funding Transportation in the Dark? The Case Study of Ontario, Canada.

The challenges of funding transportation infrastructure and services are significant and they shape both what is built and how individuals travel. Transportation funding sources are evolving considering changing technologies. The case study of Ontario, Canada, which is in the process of a generational investment in transit infrastructure, illustrates opportunities for addressing these challenges.

A Bichromophoric Triazatruxene Tetrad as a Highly Tunable Multicolor Emitter and Its Application in OLEDs.

We report on the new star-shaped triazatruxene (TAT) tetrad 1, where three peripheral TAT moieties connect to a central TAT through propargylic spacers. The insulating nature of the linkers results in separate, partially overlapping blue and yellow-orange emissions from the peripheral and central TATs. This renders 1 a multicolor emitter, whose emission color can be tuned by the choice of the excitation wavelength and the solvent.