Dosing of intravenous alprostadil in neonates with ductal-dependent CHD.

Introduction: Neonates with ductal-dependent CHD rely on the patency of the ductus arteriosus to maintain circulation. Alprostadil is utilised to maintain ductal patency, although optimal dosing has not been determined. This study aims to describe alprostadil dosing in neonates with ductal-dependent CHD.

Are You as Tired as I Am? Mental Fatigue Perception in Female Australian Rules Football Athletes Over a Season: The Influence of Personality.

Purpose: Research on mental fatigue and its impact on sport performance has gained significant attention in sport science. A reoccurring observation in these studies is the variation among participants in terms of mental-fatigue perception, as well as impact on performance. Thus, this study investigated personality traits as moderators of these interindividual differences.

Microvascular preservation & cardiomyocyte hyperplasia underlie adaptive right ventricle development in congenital heart disease-pulmonary arterial hypertension.

Right ventricular (RV) failure is the primary cause of death among patients with pulmonary arterial hypertension (PAH). Patients with congenital heart disease-associated PAH (CHD-PAH) demonstrate improved outcomes compared to patients with other forms of PAH, which is related to the maintenance of an adaptively hypertrophied RV. In an ovine model of CHD-PAH, we aimed to elucidate the cellular, microvascular, and transcriptional adaptations to congenital pressure overload that support RV function.

Kim's Lesion of the Shoulder: A Critical Analysis Review.

» Kim's lesion of the shoulder is characterized by incomplete tearing of the junction between the posteroinferior labrum and the glenoid, with the superficial labral tissue remaining intact, and generally requires arthroscopic evaluation for accurate confirmation.» Kim's lesion represents an under-reported subtype of posterior labral injury and a source of activity-related posterior shoulder discomfort and instability.» Kim's lesions are frequently observed in young, active individuals involved in overhead and contact sports, often resulting from traumatic mechanisms with the shoulder in flexion and adduction, as well as from repetitive microtrauma and overuse.

Events in the stream of behavior.

The human mind constructs and updates models of events during comprehension. Event models are multidimensional, multi-timescale, and structured. They enable prediction, shape memory formation, and facilitate action control.