Bacteria-Mitochondria Cross-talk: How Microbes Regulate Mitochondrial Dynamics and Bioenergetics of Host Cells.

Mitochondria are the cellular powerhouses and are considered to be central to energy metabolism, dynamics, and homeostasis. There is growing evidence that the gut microbiome regulates mitochondrial biogenesis, dynamics (fission, fusion, mitoph-agy), and bioenergetics, and that it does so by connecting bacterial metabolites and signaling molecules. This review discusses the molecular mechanisms that underlie the interplay between bacteria and mitochondria, with a particular focus on the modulation of mitochondrial activities by microbial products, including bile acids, immunological mediators, and short-chain fatty acids (SCFAs).

Early-Life Microbiome and Neurodevelopmental Disorders: A Systematic Review and Meta-Analysis.

Background And Objectives: This systematic review intends to find out how neurodevelopmental disorders, including Attention Deficit Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD), are influenced by the gut microbiota throughout early childhood. The study looks at the variety and types of microbes that a child is exposed to, the particular microbiome profiles associated with neurodevelopmental outcomes, and the molecular processes that underlie these relationships.

Methods: We performed a thorough search of PubMed, Scopus, the WHO Global Health Library (GHL), and ISI Web of Science.

Genomic Face-off: An Comparison of the Probiotic Potential of spp. and .

Introduction: The gut microbiota plays a crucial role in maintaining human health, and probiotics have gained significant attention for their potential benefits. Among the diverse array of gut bacteria, and spp. have emerged as promising candidates for their putative probiotic properties.

Draft genome sequence of AZLM01 isolated from chicken sausage in Bangladesh.

is a food-borne pathogen that poses a significant risk of severe infections, especially in pregnant women, the elderly, and immunocompromised individuals. This report presents the draft genome sequence of strain AZLM01, isolated from ready-to-eat chicken sausage-a food item that has recently gained popularity in Bangladesh.

Microbial Influences: The Microbiome's Impact on Pancreatic Cancer Development and Progression.

Pancreatic ductal adenocarcinoma (PDAC) presents significant challenges due to its dense stromal environment, which impedes treatment efficacy. Recent molecular and phenotypic analyses have enhanced our understanding of PDAC, driving the development of targeted therapies. Emerging research highlights the crucial role of the pancreatic tumor microbiome in PDAC initiation and progression.