Adapt Phys Activ Q
August 2025
One role of adapted physical educators is connecting with parents of children with disabilities to enhance service delivery. However, parents experience a disconnect with teachers. Much of the literature has focused on parent perspectives, but equally important is understanding the perspectives of teachers.
View Article and Find Full Text PDFBackground: Clinical stage III melanoma has a high recurrence rate following surgical dissection. The use of neoadjuvant treatment has been shown to improve long-term outcomes when compared with up-front surgery, with the pathological response being the best predictor. Biomarkers predicting responses and possibly allowing surgical de-escalation are missing.
View Article and Find Full Text PDFPurpose: Neoadjuvant ± adjuvant immunotherapy improves event-free survival (EFS) versus adjuvant immunotherapy alone for high-risk resectable Stage III melanoma. However, the optimal regimen balancing efficacy and tolerability is unknown. T-cell immunoglobulin and ITIM domain (TIGIT) is a promising immune checkpoint whose therapeutic potential in Stage III melanoma is underexplored.
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