Background: Ankyloglossia is a lingual frenulum alteration that restricts tongue movements and may be related to breastfeeding difficulties. This study aimed to determine the estimated proportion of ankyloglossia among infants with breastfeeding difficulties.
Methods: The protocol was registered in PROSPERO (#CRD42023394743).
J Oral Pathol Med
August 2025
Background: Odontogenic keratocyst (OKC) treatment often involves enucleation followed by peripheral ostectomy to reduce recurrence. However, identifying bone areas containing epithelial remnants remains a surgical challenge. The intraoperative use of 1% methylene blue solution has been proposed to delineate residual epithelial tissue.
View Article and Find Full Text PDFInt J Paediatr Dent
July 2025
Background: Mouth breathing may lead to changes in the oral cavity.
Aim: To compare dental caries and periodontal outcomes in children and adolescents with and without mouth breathing.
Design: This systematic review, registered in PROSPERO (CRD42024536891), included the following: Population: children and adolescents; Exposure: mouth breathing; Comparison: non-mouth breathing; Outcome: dental caries and periodontal/gingival conditions; Study design: observational studies.
Head Neck Pathol
July 2025
Purpose: To evaluate the role of oxidative DNA damage, cell proliferation, and apoptosis in oral leukoplakia (OL) and oral squamous cell carcinoma (OSCC) in patients aged 40 years or younger.
Methods: Sixty-four OL, twenty-eight OSCC and ten normal oral mucosa (NOM) were subjected to immunohistochemistry evaluation of 8-OhDG, Ki-67, Bax, and Bcl-2 using formalin-fixed, paraffin-embedded tissue sections. For the analysis of immunostaining, the immunoreactive score was used for the 8-OhDG, Bax, and Bcl-2 biomarkers, while the labeling index was calculated for Ki-67 quantification.
Oral Surg Oral Med Oral Pathol Oral Radiol
June 2025
Objective: To analyze the clinicopathological profile of aneurysmal bone cysts (ABCs) in gnathic bones in a Brazilian population through a multicenter study and literature review.
Study Design: A retrospective study across six Brazilian centers for oral and maxillofacial pathology collected data on sex, age, pain, location, radiographic features, and associated lesions. A literature review was performed using four databases.
ObjectiveTo investigate the impact of nasoalveolar molding (NAM) treatment after cheiloplasty surgery on the results of nasal symmetry in individuals with cleft lip and/or cleft palate (CL/P).DesignSystematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.SettingElectronic searches were performed in 6 databases in October 2023.
View Article and Find Full Text PDFObjectives: Sjögren disease (SD) is a chronic autoimmune disorder that primarily affects the exocrine glands, often resulting in significant oral health complications, such as dental caries and periodontal disease. Tooth loss, a potential consequence of these conditions, has not yet been conclusively associated to SD. This systematic review, meta-analysis, and meta-regression aimed to determine whether individuals with SD exhibit higher tooth loss compared to healthy controls.
View Article and Find Full Text PDFAims: Tricho-dento-osseous syndrome (TDOS), a rare autosomal dominant condition caused by mutations in DLX3, is characterized by abnormalities in teeth, bone, and hair. This systematic review and meta-analysis summarized the most frequently reported dento-craniofacial features of TDOS.
Methods: Searches were undertaken in five databases supplemented by manual scrutiny and a gray literature search.
This study aimed to assess the psychometric properties of the Brazilian version of the Patient Satisfaction Questionnaire (PSQ) which assesses the satisfaction of adolescents with orthodontic treatment. The PSQ is a 58-item self-report instrument presenting six subscales (doctor-patient relationship, situational aspects, dentofacial improvement, psychosocial improvement, dental function, and a residual category). The psychometric properties of the Brazilian version of the PSQ (B-PSQ) were assessed in a cross-sectional study with 111 adolescents between 11-18 years who had undergone orthodontic treatment.
View Article and Find Full Text PDFOral melanoma is an aggressive neoplasm arising from melanocytes in the mucosal epithelium, accounting for 0.2%-0.8% of all melanomas.
View Article and Find Full Text PDFPreventive maintenance in pediatric dentistry is essential for monitoring oral health and promoting healthy habits. This study aimed to evaluate how the frequency of follow-up appointments, as well as sex- and age-related differences, impact the probability of referral for curative treatment among pediatric dentistry patients at a Brazilian dental school. This retrospective longitudinal study included dental records of patients who had their first appointment between the second half of 2013 and the second half of 2019, completed treatment, and returned for at least one check-up visit.
View Article and Find Full Text PDFJpn Dent Sci Rev
December 2025
This review aimed to evaluate the efficacy of different interventions used on the palatal donor area in the treatment of postoperative pain after free gingival graft and connective tissue graft techniques, and their impact in the oral-health related quality of life (OHRQOL). This study was conducted according to PRISMA. A search was conducted in four electronic databases and the grey literature.
View Article and Find Full Text PDFHead Neck Pathol
March 2025
Background And Purpose: Described in 2013, intraneural pseudoperineuriomatous proliferations (IPP) present perineurial cells concentrically surrounding the axon-Schwann cell complexes, forming pseudo-onion bulbs. Different from intraneural perineuriomas, rare neoplasms with differentiation of perineural cells, IPP are reactive, associated with fibrosis, and frequently diagnosed histologically as traumatic neuroma (TN). The aim of this study was to characterize IPP by exploring its clinicopathological features and differentiating it from the main neural lesions that are part of the histopathological differential diagnosis through a retrospective study in six Brazilian Oral Pathology laboratories.
View Article and Find Full Text PDFOral health-related quality of life (OHRQoL) is a critical measure for assessing the impact of orthodontic treatments, including aligners. This study aimed to investigate factors associated with OHRQoL among orthodontic aligner wearers. This cross-sectional study included 34 participants.
View Article and Find Full Text PDFThe use of aromatase inhibitors (AIs) leads to an imbalance in bone remodeling and can cause osteoporosis. This study aimed to identify clinical, periodontal, nutritional, and biochemical determinants of bone mineral density (BMD) changes in patients using AIs. The sample consisted of 40 women using AIs and 32 controls.
View Article and Find Full Text PDFJ Autism Dev Disord
February 2025
This systematic review and meta-analysis aimed to assess and compare the prevalence of dental caries in children and adolescents with and without ASD and identify associated factors. Following the PRISMA guidelines, a comprehensive literature search was conducted across multiple databases, yielding 2,103 studies, from which 25 met inclusion criteria. The primary outcome measure was caries prevalence, analyzed through clinical assessments.
View Article and Find Full Text PDFAn association between bruxism and musculoskeletal disorders, such as neck pain, has been established. This study investigated the association of possible sleep bruxism (PSB) activities, including grinding, bracing, and thrusting, with smartphone use, smartphone-induced neck pain, and sleep features. This cross-sectional study involved 403 Brazilian adolescents aged 11 to 19 years.
View Article and Find Full Text PDFJ Oral Pathol Med
March 2025
Background: Cosmetic injections are increasing, as their complications, which can be misdiagnosed as neoplastic lesions. This study aimed to detail clinical, pathological, histochemical, and immunohistochemical features of adverse reactions to cosmetic fillers in the oral and maxillofacial region.
Methods: Samples were retrieved from five pathology laboratories.
Oral Surg Oral Med Oral Pathol Oral Radiol
May 2025
Objective: To describe the characteristics and outcomes of a cohort of patients with oral vascular anomalies (OVA) treated with sclerotherapy using 5% ethanolamine oleate at a dosage of 0.1 mL per 10 mm of lesion size.
Study Design: Sixty-seven patients were selected from a review of 300 medical records of individuals who had been diagnosed with OVA.
Spec Care Dentist
January 2025
Aims: Kallmann syndrome (KS) is a rare genetic disorder characterized by congenital hypogonadotropic hypogonadism and varied clinical features. Despite its recognition, the oral and maxillofacial manifestations remain poorly understood. This study synthesized clinical aspects and management of KS-related oral and maxillofacial alterations.
View Article and Find Full Text PDFThere is an interaction between dendrocytes and mast cells in the skin. However, in elastosis-related diseases such as actinic cheilitis (AC) and lower lip squamous cell carcinoma (LLSCC), this interaction remains unknown. We investigated the presence of intact and degranulated mast cells in AC and LLSCC.
View Article and Find Full Text PDFOdontology
July 2025
Introduction: Leukemia and lymphoma mimicking periapical conditions can lead to significant diagnostic pitfalls. Guidance for endodontists in managing such cases is barely explored. This systematic review aimed to summarize the clinicopathologic, imaging, and management aspects of leukemia/lymphoma that mimicked periapical conditions and resulted in endodontic treatment.
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