Predictive Capacity of the Integrated Care for Older People Screening Tool to Assess Fall Risk in Older Adults in Geriatric Care.

Aim: To evaluate the predictive capacity of the Integrated Care for Older People screening tool for the risk of falls in older people receiving care at a healthcare service.

Design: A cross-sectional study.

Method: This study was conducted in a geriatric healthcare service in the southeast region of Brazil.

Exploring the Impacts of High-Intensity Interval Training (HIIT) in People Living with HIV: A Scoping Review.

People with human immunodeficiency virus (PWH) face increased health risks beyond those directly linked to HIV infection, including reduced cardiorespiratory fitness (CRF), cardiovascular disease, and accelerated aging. Physical exercise, particularly high-intensity interval training (HIIT), may help mitigate these issues. This scoping review aimed to map the current evidence on the effects of HIIT in PWH.

Educational technologies on signs of gestational risk and/or labor for pregnant women: a scoping review.

Objective: To map educational technologies on signs of gestational risk and/or labor developed or used to guide pregnant women in the context of Brazilian prenatal care.

Method: Scoping review conducted in accordance with JBI with searches performed in the following databases: Scopus, Web of Science, PubMed/MEDLINE, LILACS, BDENF, BDTD, and Google Scholar, without time restriction. Data selection and extraction in independent stages by pairs, and narrative synthesis according to the PAGER model.

Exercise-induced effects on atherogenesis and tryptophan catabolism via the kynurenine pathway in an HIV-associated atherosclerosis mouse model.

A mouse model of HIV-associated atherosclerosis (Tg26ApoE) exhibited increased plaque area compared with the ApoE mouse, linked to elevated indoleamine 2,3-dioxygenase (IDO) activity. IDO catalyses the conversion of tryptophan (TRP) into kynurenine (KYN), measured by the KYN-to-TRP ratio. As a biomarker of inflammation, IDO has been implicated as a risk factor for cardiovascular disease.

Merging Natural Biopolymers with Supramolecular Chemistry: Emulating the Native Extracellular Matrix's Complexity.

The extracellular matrix (ECM) is one of the most striking natural self-assembled landscapes, essential for tissue integrity and cellular functions, where it orchestrates cell fate through a dynamic interplay of noncovalent interactions. Despite decades of research, there is still no scaffold that can replicate its nanostructural elegance and functional dynamic behavior. In this Perspective, we summarize cutting-edge approaches to reconstruct the ECM, putting an emphasis on either dynamic supramolecular designs or naturally sourced biopolymers.