Molecular identification of (Diptera: Culicidae) using internal transcribed spacer 2.

Background: is a widespread mosquito species in sub-Saharan Africa. It is a potential vector for human malaria parasites and has been found naturally infected with and . Morphological identification is challenging even with pristine specimens and current molecular methods such as the use of the internal transcribed spacer 2 (ITS2) polymerase chain reaction (PCR) cannot distinguish from morphologically similar .

CHP1 promotes lipid droplet growth and regulates the localization of key enzymes for triacylglycerol synthesis.

The glycerol-3-phosphate (G-3-P) pathway is central to the synthesis of triacylglycerols (TAGs) and glycerophospholipids, essential for membrane biogenesis and lipid storage. The first and rate-limiting step in this pathway is catalyzed by glycerol-3-phosphate acyltransferases (GPATs), with microsomal GPAT3 and GPAT4 being evolutionarily conserved and predominant in most tissues. While previous studies have implicated Calcineurin B homologous protein 1 (CHP1) as a cofactor for GPAT4, the broader role of CHP1 in regulating microsomal GPATs and TAG biosynthesis remains unclear.

Characterizing BOLD activation patterns in the human hippocampus with laminar fMRI.

The human hippocampus has been extensively studied at the macroscale using functional magnetic resonance imaging (fMRI) but the underlying microcircuits at the mesoscale (i.e., at the level of layers) are largely uninvestigated in humans.

Normative trajectories of R , R *, and magnetic susceptibility in basal ganglia on healthy ageing.

Quantitative MRI (qMRI) techniques, including R, R*, and magnetic susceptibility mapping, have emerged as promising tools for generating surrogate imaging markers of brain tissue microstructure, enabling non-invasive in vivo measurements associated with myelination and iron deposition. Gaining insights into how these quantitative measurements evolve throughout a normal lifespan can enhance our understanding of brain maturation processes and facilitate studies of disease-related microstructural changes by distinguishing pathological alterations from normal brain development. In this study, we established the normative trajectories of R, R*, and magnetic susceptibility in the basal ganglia at 3T.

Time-resolved instantaneous functional loci estimation (TRIFLE): Estimating time-varying allocation of spatially overlapping sources in functional magnetic resonance imaging.

In functional magnetic resonance imaging, multivariate proxies of functional brain networks are commonly extracted using spatial independent component analysis. The theoretical premises of spatial overlap among functional processes and the time-varying nature of functional connectivity prompt the question of how to accurately model spatially overlapping and time-varying functional sources. Well-known functional networks have previously been shown to divide into spatially overlapping and functionally distinct subprocesses termedusing temporal independent component analysis on the time courses obtained via spatial independent component analysis.