Building the Foundation for Standardized Care Metrics in Jejunoileal Atresia: A Systematic Review of Reported Baseline Characteristics, Treatment Variables and Outcomes.

: An evidence-based list of key variables regarding jejunoileal atresia (JIA) care needs to be established to enable quality evaluation and optimization of its care. The aim of this study is to provide an overview of reported patient, treatment, and outcome variables for JIA as documented in recent literature. This list has not been developed previously and will be the foundation for a JIA quality indicator set of the European Pediatric Surgery Audit (EPSA).

Fidelity, Implementation Determinants, and Patient-Level Outcomes Following Initial Implementation of NAVIGATE in the Early Psychosis Intervention-Spreading Evidence-Based Treatment (EPI-SET) Study.

Background And Hypothesis: While early psychosis intervention (EPI) services are effective, care delivery is often inconsistent, particularly in recovery-oriented care. We hypothesized that facilitated implementation of NAVIGATE, an evidence-based, standardized model of coordinated specialty care, would increase fidelity to EPI standards and improve patient functioning in real-world settings.

Study Design: The Early Psychosis Intervention-Spreading Evidence-based Treatment (EPI-SET) study was a non-randomized effectiveness-implementation hybrid type III trial in 6 Ontario EPI programs.

Characterization of NTS-to-VTA projection neurons reveals higher-order synaptic organization and distinct responsiveness to cholecystokinin.

The midbrain ventral tegmental area (VTA) shapes goal-oriented behaviours, including food intake, via dense dopaminergic projections to many key forebrain areas. In addition, the VTA serves as an integrator of neural inputs from throughout the brain that modulate VTA output to produce broad, state-dependent, changes that reflect the balance of internal and external considerations. The brainstem nucleus of the solitary tract (NTS) is the primary site for integration of viscerosensory and taste information conveyed through the cranial nerves and is essential for the control of food intake.

Core Indicator Set for Measuring Quality of Care in Necrotising Enterocolitis: A European Delphi Study.

Aim: Inconsistent guidelines and practice variations in necrotising enterocolitis (NEC) hamper care improvements. A universally accepted quality indicator set is needed to standardise and improve care throughout Europe. We aimed to establish a core set relevant to NEC patients and experts.