Publications by authors named "D Ramonfaur"
Article Synopsis
- A study assessed the real-world effectiveness of mavacamten for treating obstructive hypertrophic cardiomyopathy in a diverse patient population at Johns Hopkins HCM center, involving 66 patients.
- Over a median treatment duration of 9 months, 72% of patients experienced improved heart failure symptoms and significant reduction in left ventricular outflow tract obstruction after 6 months of treatment.
- The medication had no severe adverse events but was less effective in patients with a BMI of 35 kg/m² or higher; effectiveness and safety were consistent across racial groups.
Importance: Heart failure (HF) and frailty frequently coexist and may share a common pathobiology, although the underlying mechanisms remain unclear. Understanding these mechanisms may provide guidance for preventing and treating both conditions.
Objective: To identify shared pathways between incident HF and frailty in late life using large-scale proteomics.
People with long COVID are those who still have symptoms, signs, and conditions after the initial phase of infection of SARS-CoV-2. The incidence of long COVID varies among regions-31% in North America, 44% in Europe, and 51% in Asia, which is challenging the healthcare system, but there is limited guidelines for its treatment. With more and more nationwide projects funded by the government such as the RECOVER initiative in the United States and National Institute for Health Research funding in the United Kingdom, an increasing number of ongoing clinical trials are investigating the efficacy of diverse therapies on reversing long COVID.
View Article and Find Full Text PDFBackground: Vaccine hesitancy (VH) is a recognized threat to public health that undermines efforts to mitigate disease burden. This study aims to gather available evidence regarding COVID-19 VH in Mexico, estimate the prevalence of VH, and its determinants to inform policymaking in this country.
Methods: Following PRISMA guidelines, a systematic review of the MEDLINE literature, articles that estimated the prevalence of COVID-19 VH in Mexico were included in the analysis to obtain a pooled estimate.