assembly of seven multidrug-resistant (MDR) Staphylococci genomes from biofilms of hemodialysis tunneled cuffed catheter tips of patients undergoing renal failure treatment.

CHRFS5, HL_CHRU_S18, S48B, HL_CHRU_S16, S19, HL_CHRU_S79, and HL_CHRU_S111 were isolated from the biofilm of catheter tip of renal failure patients. Whole genome sequencing predicted the presence of multiple antibiotic-resistant gene cassettes.

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration-resistant prostate cancer.

Prostate cancer (PCa) is the second most lethal cancer in men in the US. African American (AA) men have twice the incidence and death rate of European American (EA) men. Advanced PCa shows increased expression and activity of the DNA damage/repair pathway enzyme, poly (ADP-ribose) polymerase 1 (PARP1).

Scleral Lens and Suture Erosion in Scleral-Sutured Posterior Chamber Intraocular Lens.

This case series reports two cases of scleral lens (SL)-associated suture erosion of polytetrafluoroethylene CV-8 (Gore-Tex, Newark, DE) in scleral-sutured CZ70BD (Alcon, Fort Worth, TX) posterior chamber intraocular lens (SS-PCIOL). Suture erosion after SS-PCIOL has been reported in two of the patients who were fitted with SL for visual acuity improvement. Erosion was corrected in both cases with suture repositioning and corneal patch graft, with one patient requiring the exchange of the intraocular lens.