Age and gender intersectionality among African Americans: Salivary uric acid is associated with shorter telomere length in younger adults and men.

Age related diseases present disproportionately among African Americans and have been tied to broad social inequalities and accompanying stress. Yet, there is considerable variability among African Americans in susceptibility, highlighting potential connections to both intersectionality and stress-related biological processes. A growing body of research links exposure to racism and discrimination to telomere length (TL)-an indicator of biological aging that is increasingly implicated in explaining stress-related racial health disparities.

Physiological attunement and flourishing: understanding the influence of relationships on health.

Background: Flourishing can be defined as the experience of life going well, a combination of feeling good and functioning effectively. High-quality relationships are essential to flourishing and long-term health. Physiological interdependence-such as synchronization of autonomic and endocrine systems-has been proposed as a mechanism supporting emotion regulation and social bonding.

Psychological and Physical Health of a Preterm Birth Cohort at Age 35 Years.

Importance: The US's longest-running preterm birth cohort study is nearing its 40th anniversary. With rising survival rates for preterm birth, understanding adult health outcomes is essential; early life medical risk trajectories are hypothesized to lead to poorer outcomes by age 35 years.

Objective: To examine how early life medical risk is associated with psychological and physiological health in adulthood, highlighting the supportive roles of social protection and childhood socioeconomic status (SES).

The salivary metabolome of children and parental caregivers in a large-scale family environment study.

Human metabolism is complex, and is impacted by genetics, cohabitation, diet, health, and environmental inputs. As such, we applied untargeted LC-MS metabolomics to 1425 saliva samples from a diverse group of elementary school-aged children and their caregivers collected during the Family Life Project, of which 1344 were paired into caregiver/child dyads. We compared metabolomes within and between homes, performed population-wide "metabotype" analyses, and measured associations between metabolites and salivary biomeasures of inflammation, antioxidant potential, environmental tobacco smoke (ETS) exposure, metabolic regulation, and heavy metals.

Prospective Associations Between Salivary Biomarkers of Inflammation and Body Mass Index in Adolescents.

Background: Childhood and adolescent obesity, which affects nearly 1 in 5 youth in the US, presents a pressing public health concern. Obesity is linked to chronic low-grade inflammation, which exacerbates comorbidities. Noninvasive tools are needed to monitor obesity-related inflammation and assess weight-management interventions in children and adolescents.