Long-term prognosis after acute coronary syndrome due to de novo coronary artery lesions and stent thrombosis in patients on hemodialysis.

Percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS) undergoing hemodialysis (HD) remains challenging, with limited long-term outcome data. We investigated the long-term prognosis of ACS due to de novo coronary artery lesions and stent thrombosis (ST) in patients with and without HD. We analyzed 187 patients with ACS from the Osaka Cardiovascular Conference Long ST registry, a retrospective, multicenter registry of definite ST, and 1,856 patients with ACS due to de novo coronary artery lesions at Kansai Rosai Hospital.

Estimation of Coronary Obstruction Risk for the Transcatheter Aortic Valve Implantation in Surgical Aortic Valve (TAV-in-SAV) Procedure.

Background: To consider transcatheter aortic valve-in-surgical aortic valve (TAV-in-SAV) as a secondary intervention, the risk of coronary obstruction during future TAV-in-SAV should be assessed prior to initial SAV replacement (SAVR), especially in Japanese patients with a small body size and aortic root anatomy. In this study we simulated the risk of coronary obstruction and identified associated anatomical factors.

Methods And Results: We retrospectively analyzed pre- and post-SAVR computed tomography scans of 115 patients and simulated the risk of coronary obstruction.

Nonreciprocal transport in a room-temperature chiral magnet.

Chiral magnets under broken time-reversal symmetry can give rise to rectification of moving electrons, called nonreciprocal transport. Several mechanisms, such as the spin fluctuation-induced chiral scattering and asymmetry in the electronic band dispersion with and without the relativistic spin-orbit interaction, have been proposed, but clear identification and theoretical description of these different contributions are desired for full understanding of nonreciprocal transport phenomena. Here, we investigate a chiral magnet CoZnMn and find the nonreciprocal transport phenomena consisting of different contributions with distinct field and temperature dependence across the magnetic phase diagram over a wide temperature range including above room temperature.

Clinical Phenotypes of Patients With Ischemic Cardiomyopathy After Percutaneous Coronary Intervention.

Background: Percutaneous coronary intervention (PCI) is a good option for patients with ischemic cardiomyopathy (ICM) at high operative risk. However, evidence shows little benefit of PCI, potentially due to heterogeneity in ICM. Here, we applied latent class analysis (LCA) to clinical data to characterize ICM phenotypes based on clinical features and to assess differences in clinical outcomes.