Electrospun chitosan nanofibers for regenerative wound healing: from molecular design to functional scaffolds.

The management of acute and chronic wounds remains a clinical challenge due to infection, delayed re-epithelialization, and impaired angiogenesis. Electrospun nanofibrous scaffolds have emerged as promising biomaterials, offering high surface area-to-volume ratios, tunable porosity, and ECM-like architectures. Chitosan, derived from chitin, is a biocompatible, biodegradable, and antimicrobial natural polymer ideally suited for wound healing.

Expression profiling, phenomics, and metabolomics revealed biochemical pathways regulating silicon induced tolerance to metalloid (As, Sb, Ge) toxicity in mungbean (Vigna radiata L. Wilczek).

Metalloid toxicity is one of the principal abiotic stresses faced by plants, leading to the uptake of harmful metalloids disrupting photosynthetic apparatus, interfere with metabolic pathways, and induce oxidative stress. The study evaluates the role of silicon (Si) in mitigating metalloid toxicity by assessing its effect on photosynthetic efficiency, antioxidant defense mechanisms; and overall physiological responses in mungbean (Vigna radiata (L.) Wilczek).

Generation of an induced pluripotent stem cell line from a malignant melanoma patient who developed the immune checkpoint inhibitor-related myasthenia gravis, myositis, and myocarditis overlap syndrome.

Immune checkpoint inhibitors (ICI) are a pivotal class of immuno-oncology therapeutics that have improved survival rates for patients with cancer. Their widespread usage, however, is limited due to the development of serious and potentially deadly ICI-related side effects. To develop novel diagnostic and therapeutic strategies to identify and treat patients at risk, we need a better understanding of the underlying mechanisms mediating these potentially deadly side effects.

Performance prediction of a two-port terahertz-based graphene-silicon-based tunable antenna with polarization and pattern diversity features using machine-learning algorithms.

This paper proposes a hybrid twin-port radiator with polarization and pattern diversity features in the terahertz (THz) frequency domain. Three major contributions of the proposed antenna design are: (i) a rounded wave is obtained by stimulating the silicon ceramic via a fan blade formed slot; (ii) a mirror orientation of aperture and suspension of partially reflecting surface (PRS) helps to get better isolation with an S-component and far-field component, respectively; and (iii) the random forest and XGBoost technique predicts the | | of the designed aerial effectively. A coating of graphene over silicon dielectric makes the radiator tunable.

A Review on Blood Flow Simulation in Stenotically Diseased Arteries.

Heart diseases which can lead to stroke and heart attacks, affect numerous individuals worldwide due to disruptions in blood flow within the body. A common underlying cause for such hemodynamic disorders is a constriction in the artery, which is known as a stenosis, which is attributable to a range of causes including atherosclerosis or plaque accumulation. Many theoretical and computational studies have been presented in this area providing a useful compliment to experimental (clinical) studies.