Longitudinal correlation between X-ray and MRI findings in medial compartment knee osteoarthritis: Insights into early cartilage loss and structural changes.

Purpose: Knee osteoarthritis (OA) is a common joint disorder assessed using radiographic (X-ray) and magnetic resonance imaging (MRI). While X-rays are accessible, MRI provides detailed insights into meniscus and cartilage. Few studies have evaluated the correlation between X-ray and MRI findings in knee OA longitudinally.

Biosynthesis of biologically active terpenoids in the mint family (Lamiaceae).

Covering: 2000 to 2025The Lamiaceae family, the sixth largest among angiosperms, is renowned for its rich diversity of terpenoids, many of which exhibit remarkable bioactivities, including anti-inflammatory, psychoactive, anti-cancer, and antiviral effects. Notable examples with fully elucidated biosynthetic pathways include menthol from peppermint, forskolin from blue spur flower, and carnosol from rosemary. For other key Lamiaceae terpenes-such as the anti-cancer oridonin, the psychoactive salvinorin A, and bioactive marrubiin and vitexilactone-significant progress has been made.

External Validation of a Novel Landmark-Based Deep Learning Automated Tibial Slope Measurement Algorithm Applied on Short Radiographs Obtained in Patients With ACL Injuries.

Background: Deep learning algorithms can aid medical decision-making by performing routine tasks without any human error. Reading of standardized radiographs lends itself well to a computerized approach. The posterior tibial slope is increasingly recognized as a factor in lower leg biomechanics.

Automated Posterior Tibial Slope Measurement Using Lateral Knee Radiographs: A Novel Landmark-Based Approach Using Deep Learning.

Background: A single universally accepted protocol does not exist for measuring the posterior tibial slope (PTS), limiting the application of cutoff values for surgical decision-making and risk stratification.

Purpose/hypothesis: This purpose of this study was to validate an online computer vision model using anatomic landmarks for PTS measurement on uncalibrated lateral knee radiographs. It was hypothesized that this model would achieve similar accuracy to manual measurement.