Posterior leaflet reconstruction in mitral valve repair: Does resect versus respect strategy matter?

Objective: Previous randomized controlled trials demonstrated comparable outcomes between posterior leaflet resections and neochord implantation in mitral valve (MV) repair. However, these studies were limited up to 1-year follow-up, and more recent evidence suggested that leaflet resections may offer superior long-term outcomes.

Methods: All patients who underwent MV repair with either resection or neochord implantation for posterior leaflet pathology between October 2011 and July 2024 were included.

Impact of ASXL1 at diagnosis in patients with CML receiving frontline potent TKIs: high risk of kinase domain mutations.

Genomic profiling in chronic-phase chronic myeloid leukemia (CP-CML) patients demonstrated somatic variants in blood cancer-related genes (CGVs) and rearrangements associated with the formation of the Philadelphia-chromosome (Ph-associated rearrangements) at diagnosis, collectively termed additional genetic abnormalities (AGA). AGAs had a negative impact on failure-free survival and molecular response in imatinib-treated patients. We investigated whether treatment with more potent therapies could overcome the negative impact of AGAs at diagnosis.

Center Experience is Associated with Greater Survival following Donation after Circulatory Death Heart Transplantation.

Background: Higher center volume has been associated with improved outcomes in solid organ transplantation. However, the impact of center experience on donation after circulatory death (DCD) heart transplantation outcomes remains unclear. This study evaluates the association between cumulative DCD center experience and DCD posttransplant survival.

Small cuts, big questions: the impact of incision length in minimally invasive robotic cardiac surgery.

Introduction: Evidence on incision lengths for ports and cardiopulmonary bypass (CPB) cannulation in robotic cardiac surgery is limited. This study aimed to assess these metrics and influencing factors.

Methods: 204 patients underwent robotic mitral valve repair (MVR) (54.

Aortic root replacement with a mechanical valve conduit: A single-institutional experience.

Background: There is a lack of consensus regarding the best strategy for aortic root replacement with current guidelines supporting the use of mechanical valves in younger patients when a valve repair is not possible. We sought to describe our institutional experience with mechanical aortic root replacement.

Methods: This was a descriptive study using an institutional database of aortic root replacements with a mechanical valve composite graft performed at our center from 2010 to 2022.