The acceptability, safety, and performance of primary cervical screening through self-collected vaginal samples in an urban teaching hospital antenatal clinic setting.

This study evaluated the feasibility, safety, and acceptability of self-collected vaginal samples for human papillomavirus (HPV) testing among pregnant women in an urban teaching hospital in Malaysia. This cross-sectional study recruited pregnant women aged 30 years and above who attended antenatal care at the University of Malaya Medical Centre. Participants self-collected vaginal samples using FLOQSwabs and completed pre- and post-sampling questionnaires assessing acceptability.

Cervical screening approach of self-collection, point-of-care HPV testing, and same-day colposcopy among Aboriginal and Torres Strait Islander women in remote Western Australia (the PREVENT Project): an implementation study.

Background: Aboriginal and Torres Strait Islander women can face substantial cancer screening barriers in remote areas. To support WHO cervical cancer elimination targets, we evaluated a novel screening approach integrating self-collection, point-of-care human papillomavirus (HPV) testing, and same-day specialist assessment for Aboriginal and Torres Strait Islander women in remote Western Australia.

Methods: We developed a screening approach using point-of-care HPV testing on self-collected samples with same-day results and immediate specialist assessment.

Microhaplotype deep sequencing assays to capture Plasmodium vivax infection lineages.

Plasmodium vivax elimination is challenged by dormant liver stages (hypnozoites) that can reactivate months after initial infection resulting in relapses. Relapsing infections confound antimalarial clinical efficacy trials due to the inability to distinguish between recurrences arising from blood-stage treatment failure (recrudescence), reinfection or relapse. Genetic relatedness of paired parasite isolates, measured by identity-by-descent (IBD), can provide important information on whether individuals have had single or multiple mosquito inoculations, thus informing on recurrence origin.

Factors influencing healthcare practitioners' decision to offer (or not) the choice of self-collection cervical screening in general practice in Victoria, Australia.

Background And Objectives: In July 2022, a policy change was enacted in the National Cervical Screening Program (NCSP) to allow all women and people with a cervix (hereafter people) the choice of a self-collected sample. This study aimed to understand healthcare practitioners' decisions, and factors related to, the provision (or not) of this change.

Method: Semi-structured interviews (n=28) were conducted between February and July 2023 with general practitioners, nurses and practice managers.

Exponential uptake of HPV self-collected cervical screening testing 2 years since universal availability in Victoria, Australia.

Background: Australia is working towards eliminating cervical cancer as a public health issue by 2035, by achieving an incidence rate of less than 4 cases per 100,000 people. Increasing cervical screening participation, particularly in under-screened groups, is critical to achieving this goal equitably. On 1 December 2017, the National Cervical Screening Program (NCSP) transitioned from two-yearly Papanicolaou smear-based screening to five-yearly primary human papillomavirus (HPV) based cervical screening tests (CST) for all women and people with a cervix aged 25-74 years.