"String Cheese" Partial Radial Artery Avulsion in a Patient Undergoing Cardiac Catheterization and Percutaneous Coronary Intervention: String Cheese Avulsion.

Background: Radial artery avulsion (RAV) is a rare but potentially serious complication of transradial angiographic procedures.

Case Summary: We describe a 70-year-old man who presented with atypical chest discomfort and who underwent cardiac catheterization from the right radial artery. The patient had radial artery spasm, and a piece of tissue approximately 6 cm in length was pulled out of the sheath.

Is bedtime use of kratom (Mitragyna speciosa) a sleep aid or disruptor? Examining its daily effects and individual differences.

Kratom () is a psychoactive botanical native to Southeast Asia increasingly used in the United States for various self-reported benefits, including sleep improvement. However, empirical evidence concerning kratom's effects on sleep is limited. Here, we examined the association between bedtime kratom use and self-reported sleep outcomes in naturalistic settings across consecutive days, while also exploring sex and chronic pain status as potential moderators.

Looking beyond traditional pain outcomes to better evaluate cannabis's true potential and limitations in chronic pain management.

Cannabis is increasingly used for managing chronic pain, despite the low quality and inconsistency of most evidence from randomized controlled trials and the divergent expert opinions and guidelines issued by academic societies. In this perspective piece, we suggest a way forward. The clinical trials have focused on traditional chronic pain outcomes (such as pain severity and interference, as well as physical and emotional functioning).

Bronchiectasis in Bronchiolitis Obliterans Syndrome after Hematopoietic Cell Transplantation.

Bronchiectasis-bronchial dilatation accompanied by impaired mucociliary clearance, chronic infection, and chronic inflammation-may contribute to poor outcomes in bronchiolitis obliterans syndrome (BOS) complicating hematopoietic cell transplantation, though its epidemiology and impact are poorly understood. We assessed factors associated with bronchiectasis in BOS. We also assessed relationships between bronchiectasis and survival, respiratory infections, and percent predicted forced expiratory volume in one second (FEV%).

A Framework for Considering the Role of the Public Sector in R&D of Health Technology.

The development of health technologies involves complex, costly, and risky investments, with significant contributions from both public and private sectors. Recent EU pharmaceutical directives propose transparency on public funding to aid pricing negotiations and affordability. However, questions remain regarding how public investments should be measured and their influence on pricing and reimbursement (P&R) decisions.