Cajanus albicans (whitish pigeon pea), native to peninsular India and Sri Lanka, is an underexplored medicinal plant traditionally used by indigenous communities in the Eastern Ghats. This study investigated the chemical composition and bioactivities of its methanolic leaf extract (CALE). Phytochemical analysis revealed high phenolic (246.
View Article and Find Full Text PDFAngiogenesis plays a critical role in cancer progression, highlighting the need for effective anti-angiogenic therapies. Zerumbone (ZER), a phytochemical compound, is known for its anti-angiogenic and anti-carcinogenic effects in various cancer cell lines. Cisplatin (CIS) is a widely used chemotherapeutic agent that effectively inhibits tumor growth.
View Article and Find Full Text PDFBreast cancer is a major cause of mortality among women worldwide, with triple-negative breast cancer (TNBC) presenting a particularly serious clinical challenge due to its low survival rates and high likelihood of recurrence. Despite the availability of several treatment options, more effective and targeted therapies are urgently needed. Chloroquine (CQ), a well-known anti-malarial drug, has recently emerged as a potential anti-cancer agent and chemo sensitizer when combined with other treatments.
View Article and Find Full Text PDFCancer is a disease marked by the uncontrolled growth and replication of cells. This study investigates the anticancer effects of the phenolic extract from (MISKPE) seed kernels on Ehrlich ascites carcinoma in Swiss albino mice. The findings highlight the therapeutic potential of MISKPE, as it reduced body weight and increased the lifespan of the mice.
View Article and Find Full Text PDFTransformerless inverters with common ground structure are favoured in grid-connected photovoltaic (PV) systems primarily due to their ability to effectively suppress leakage current, eliminate transformer-related losses, enhance efficiency, and reduce costs. A six switch seven-level (S2-7 L) common ground type triple boost transformerless inverter topology for grid-tied solar PV applications is presented in this paper. The proposed structure maintains a constant common-mode voltage by sharing a common ground point between the source and the grid neutral, so effectively suppressing leakage current.
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