Association between facility volume with treatment patterns and short-term surgical outcomes in pituitary adenoma: a National Cancer Database analysis.

Objective: Pituitary adenomas (PAs) are common intracranial neoplasms for which definitive treatment is generally transsphenoidal resection depending on patient and tumor characteristics. Recent studies have demonstrated that patients with other intracranial tumors treated at high-volume centers are more likely to undergo surgery, receive adjuvant therapy, and experience improved surgical outcomes. However, PAs have yet to be studied in this context.

Intraoperative Cerebrospinal Fluid Leaks During Endoscopic Endonasal Tumor Resection are Associated With Higher Emesis Rates and Greater Opioid Use in the Acute Postoperative Period.

Background And Objectives: Cerebrospinal fluid (CSF) leaks are common after endoscopic endonasal approach (EEA). Opioid-induced emesis in the acute postoperative period may play a role in causing these leaks. The purpose of this study was to understand the associations between opioid use, postoperative emesis, and CSF leak occurrence after EEA.

Catheter-based polarimetric imaging to complement MRI for deep brain stimulation neurosurgery.

Significance: Deep brain stimulation (DBS) is an established treatment for movement disorders and other neurological conditions. Accurate localization of small deep brain nuclei, such as the subthalamic nucleus (STN) and internal pallidum (GPi), is crucial for successful DBS outcomes. However, magnetic resonance imaging (MRI), commonly used for DBS planning, lacks the resolution and contrast needed to directly delineate these target structures.

DualSight: multi-stage instance segmentation framework for improved precision.

Powder properties, particularly their morphology (which includes size, shape, surface roughness, etc.), play a critical role in the quality of cold spray additively manufactured materials. A change in feedstock powder morphology can impact flowability and deposition quality, deposition efficiency, and porosity.

Current understanding of the role of DNA methylation in pituitary neuroendocrine tumors.

Pituitary neuroendocrine tumors (PitNETs) are unusual among neoplasms in that sporadic tumors are not typically associated with genetic mutations. Instead, epigenetics, a non-mutational process by which gene expression is modified via a variety of mechanisms, may be a driving factor in PitNET growth and behavior. DNA methylation is one of the most well-understood forms of epigenetic modification.