Effect of intraoperative paravertebral or intravenous lidocaine infusion on postoperative complications and inflammation after lung resection surgery: a randomised controlled trial.

Background: The potential for the anti-inflammatory effects of lidocaine to reduce complications after lung resection has not been evaluated. We assessed whether intraoperative i.v.

Open partial or transoral laryngectomy - total laryngectomy today.

Total laryngectomy, a surgical procedure involving the complete removal of the larynx, has been a crucial treatment for advanced laryngeal cancer since its introduction in 1873. Over the past 150 years, this procedure has evolved significantly, with improvements in surgical techniques, postoperative care, and rehabilitation methods leading to better survival rates and quality of life for patients. While organ-preserving approaches like radiochemotherapy have gained prominence in recent decades, total laryngectomy remains an essential option for cases of advanced cancer or when other treatments fail.

Development and validation of a risk prediction tool for drug-related problems in pre-operative elective surgical patients (mediPORT): A case-control study.

Background: Drug-related problems (DRP) in pre-operative care can harm patient outcomes. This study aimed to develop and validate a pre-operative risk prediction tool (mediPORT) to calculate the probability of DRP in admitted patients.

Methods: Elective surgery patients aged ≥ 18 years admitted to the pre-anaesthesia clinic and participating in a medication review by pharmacists were included in this case-control study.

When and how do 17-year periodical cicada nymphs decide to emerge? A field test of the 4-year-gate hypothesis.

The 17-year cicadas ( spp.) are renowned for the longest, strictly regulated juvenile period in insects, yet how they control their life cycle is unknown. Here, we test our hypothesis of adult emergence decision points at developmental gates of 4 years based on critical body weight (CBW).

Disparities in liver transplantation for metabolic dysfunction-associated steatohepatitis-associated hepatocellular carcinoma.

Background: Metabolic dysfunction-associated steatohepatitis (MASH) is increasingly common, as is hepatocellular carcinoma (HCC) in the background of MASH. Liver transplantation (LT) provides superior long-term survival for patients with unresectable MASH-HCC, but not all patients have equal access to transplant. MASH-HCC disproportionately affects Hispanic patients, but minorities are less likely to undergo LT for HCC.