Temporal trend and spatial analysis of breast cancer mortality in Paraná, 2012-2021.

Objectives: To analyze the temporal trend and identify spatial clusters of breast cancer mortality in Paraná state between 2012 and 2021.

Methods: This was a time series study, with spatial analysis of breast cancer mortality rates in the 399 municipalities of Paraná. Data were selected from the Mortality Information System.

Individualised connectomic-guided radiosurgical thalamotomy for chronic pain.

Introduction: Radiosurgery targeting the thalamus has long been used to treat refractory pain, with medial thalamotomy as a key approach. Traditionally, targeting relied on indirect methods based on anatomical atlases, which do not account for individual variations in brain connectivity. Recent advances in connectomic-guided stereotactic radiosurgery have improved precision in the treatment of movement disorders, but their application to pain management remains underexplored.

Molecular-level heterogeneity in deep eutectic electrolytes.

Deep eutectic electrolytes (DEEs) have in recent years gained momentum as prospective compounds for next-generation (lithium) batteries. Yet, the connection between molecular-level properties and macroscopic performance of DEEs is poorly understood. We have here, by molecular dynamics simulations, studied in detail a few simple DEEs created using the hydrogen bond (HB) donor -methyl-acetamide (NMA) and one of three different common lithium salts: LiBF, LiDFOB, and LiBOB, all in a 1 : 4 molar ratio composition.

Spirituality and psychological capital as predictors of psychological well-being in adults in Ecuador and Peru.

Background: Several studies have indicated a positive association between positive psychological resources-such as spirituality and psychological capital-and psychological well-being. However, the specific nature of these relationships remains poorly understood.

Objective: The purpose of this study was to examine, through a model of structural equations, the influence of spirituality and psychological capital on psychological well-being, as well as to explore the relationship between these two predictor variables.

Plant growth-promoting bacteria as biological control agents for sustainable agriculture: targeting root-knot nematodes.

The increasing frequency of extreme weather events affects ecosystems and threatens food production. The reduction of chemical pesticides, together with other ecological approaches, is crucial to more sustainable agriculture. Plant-parasitic nematodes (PPN), especially root-knot nematodes (RKN), spp.