Programmable memristors with two-dimensional nanofluidic channels.

Nanofluidic memristors, obtained by confining aqueous salt electrolyte within nanoscale channels, offer low energy consumption and the ability to mimic biological learning. Theoretically, four different types of memristors are possible, differentiated by their hysteresis loop direction. Here, we show that by varying electrolyte composition, pH, applied voltage frequency, channel material and height, all four memristor types can emerge in nanofluidic systems.

Microtomy-fabricated two-dimensional nano-slits enable single molecule biosensing.

Nanofluidic devices have emerged as a powerful sensor for single-molecule studies. Among these, biological nanopores have demonstrated remarkable capabilities, ranging from detecting epigenetic modifications in DNA to showing promising results for developing protein sequencing technologies. Despite extensive research, their solid-state counterparts, such as solid-state nanopores and nano-slits, have not achieved comparable success.

Slow Water in Engineered Nanochannels Revealed by Color-Center-Enabled Sensing.

Nanoscale confinement of liquids can result in enhanced viscosity, local fluidic order, or collective motion. Studying these effects, however, is notoriously difficult, mainly due to the lack of experimental methods with the required sensitivity and spatial or time resolution. Here we leverage shallow nitrogen-vacancy (NV) centers in diamond to probe the dynamics of room-temperature water molecules entrapped within ∼5 nm-tall channels formed between the diamond crystal and a suspended hexagonal boron nitride (hBN) flake.

Ovarian metastasis from lobular breast carcinoma: A case report with review of literature.

Although breast cancer can metastasize to various sites, involvement of the ovaries is infrequent. The current study aims to report a case of ovarian cancer originating from the breast along with an in-depth analysis of the literature. A 58-year-old woman with a history of invasive lobular carcinoma underwent surgery followed by adjuvant chemo-radiotherapy.

Recent Trends and Perspectives on Malaria Relapse: A Mini Review.

Worldwide elimination of malaria remains a challenge yet to be accomplished, and the domain of malaria relapse equally remains obtuse. Yet sophisticated cell culture and screening techniques and animal models are being constructed and molecular regulations are discovered in this intriguing discipline. An elaborate understanding of these schemes is mandatory to conceive effective therapeutic strategies.