Rehabilitation of Ectodermal Dysplasia Patients Presenting with Hypodontia: Outcomes of Implant Rehabilitation: Part 2: Two Cases.

Purpose: This study has assessed improvements of patients with ectodermal dysplasia (ED) and treated by a multidisciplinary team with provision of fixed prostheses supported by dental implants.

Methods: Two patients with ED and hypodontia were treated with new maxillary complete dental prostheses or fixed implant prostheses, and a mandibular fixed dental prosthesis with implants. Patients were assessed with questionnaires to evaluate improvements in function, social and psychological problems.

Dapagliflozin's Association With Cardiorenal Outcomes and Apolipoprotein M Levels in HFrEF Patients: Insights From DEFINE-HF.

Background: Apolipoprotein M (ApoM) is associated with lower mortality in heart failure (HF) patients and protects against cardiac and kidney injury in mice.

Objectives: The authors investigated dapagliflozin's cardiorenal effects by studying its association with ApoM in patients with HF with reduced ejection fraction.

Methods: We performed a secondary analysis of DEFINE-HF (Dapagliflozin Effects on Biomarkers, Symptoms, and Functional Status in Patients with HF with Reduced Ejection Fraction) to assess dapagliflozin's effects on ApoM, N-terminal pro B-type natriuretic peptide (NT-proBNP), and urine albumin-creatinine ratio (UACR) changes from baseline to 12 weeks.